Noor Omar, Elston Dirk, Flamm Alexandra, Hall Lawrence D, Cha Jisun
Department of Dermatology, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Department of Dermatopathology, Ackerman Academy of Dermatopathology, New York, NY, USA.
J Cutan Pathol. 2015 Aug;42(8):574-7. doi: 10.1111/cup.12511. Epub 2015 May 26.
Atypical acquired melanocytic nevi in patients with epidermolysis bullosa (EB) have been referred to as EB nevi and are considered to be a type of recurrent nevus with atypical but distinctive histopathologic findings. Herein, we describe an atypical nevus in a patient with Hailey-Hailey disease with different histopathologic findings from EB nevi because of presumably different pathogenesis. It is important to be aware that the recurrent nevi phenomenon can be seen in acantholytic conditions as well as blistering disorders, given these lesions may clinically resemble melanoma.
大疱性表皮松解症（EB）患者中的非典型获得性黑素细胞痣被称为EB痣，被认为是一种具有非典型但独特组织病理学表现的复发性痣。在此，我们描述了1例Hailey-Hailey病患者的非典型痣，其组织病理学表现与EB痣不同，可能是由于发病机制不同。需要注意的是，复发性痣现象可见于棘层松解性疾病以及水疱性疾病，因为这些病变在临床上可能类似于黑色素瘤。
