Vilalta J, Sahuquillo J, Benito M, Puig G, Godet C, Rubio E
Rev Esp Anestesiol Reanim. 1989 Sep-Oct;36(5):255-9.
In 130 cases of post-traumatic coma a study of multimodality evoked potentials (MEP) was carried out shortly after the traumatism (within 72 h). According to the morphology of the records they were classified in grades (I-IV) in agreement with Greenberg et al. The worst grade of EP in the different types was related to the outcome at 6 months, distinguishing between focal lesions and diffuse lesions. Only a group (22.9%) of the 109 patients in which the auditory brain-stem evoked potentials (ABEP) could be studied, showed severe disorders (grade III-IV). There was a significant correlation between the ABEP grades and the outcome in the focal lesions (p less than 0.001). In the diffuse lesions the ABEP grades did not show significant differences with the outcome. A 22.4% of the patients with diffuse lesions had some visual evoked potentials (VEP) in grades III-IV against almost the double (41.6%) in the focal lesions. The grades of the VEP in the focal lesions did not have differences with outcome and in the diffuse lesions they did (p less than 0.05). Approximately half of the cases with focal lesions and one third of the diffuse lesions showed severe disorders (grades III-IV) of the somatosensory evoked potentials (SEP). In the two types of lesions there were significant differences with the outcome (p less than 0.001) and (p less than 0.01). The multimodality evoked potentials (MEP) are useful for predicting the outcome, especially in the patients where the neurological examination is impossible. Among the different modalities, the SEP were shown to be more predictive.(ABSTRACT TRUNCATED AT 250 WORDS)
对130例创伤后昏迷患者在创伤后不久(72小时内)进行了多模态诱发电位(MEP)研究。根据记录的形态,按照格林伯格等人的标准将其分为I - IV级。不同类型损伤中最差的诱发电位级别与6个月时的预后相关,区分局灶性损伤和弥漫性损伤。在109例可研究听觉脑干诱发电位(ABEP)的患者中,只有一组(22.9%)表现出严重异常(III - IV级)。局灶性损伤中ABEP级别与预后之间存在显著相关性(p < 0.001)。在弥漫性损伤中,ABEP级别与预后无显著差异。22.4%的弥漫性损伤患者有一些III - IV级的视觉诱发电位(VEP),而局灶性损伤患者中这一比例几乎是其两倍(41.6%)。局灶性损伤中VEP级别与预后无差异,而在弥漫性损伤中有差异(p < 0.05)。大约一半的局灶性损伤病例和三分之一的弥漫性损伤病例表现出体感诱发电位(SEP)严重异常(III - IV级)。在这两种类型的损伤中,SEP与预后均存在显著差异(p < 0.001)和(p < 0.01)。多模态诱发电位(MEP)有助于预测预后,尤其是在无法进行神经学检查的患者中。在不同模态中,SEP显示出更强的预测性。(摘要截断于250字)