Department of Chronic Diseases and Injuries, French Institute for Public Health Surveillance, Saint Maurice, France.
Department of Cardiology, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
Eur J Heart Fail. 2015 Jun;17(6):583-90. doi: 10.1002/ejhf.284. Epub 2015 May 6.
The objectives of this study were to describe annual trends in patients hospitalized for heart failure (HF) and HF-associated mortality rates in France between 2000 and 2012.
Hospital discharge data were extracted from the French National Hospitalization Database (PMSI). Mortality data were obtained from the French National Mortality Database. HF events constituting the underlying or associated cause of death were selected. Rates were age standardized using the 2010 European census population as the standard population. Time trends were tested using a Poisson regression model. In 2012, the overall age-standardized rate of patients hospitalized for HF was 246.2 per 100,000 inhabitants. The age-standardized rate of HF-associated mortality was 113.8 per 100,000 inhabitants in 2010. Hospitalized patient rates remained steady between 2002 and 2012, whereas mortality decreased by 3.3% annually from 2000 to 2010. Trends in hospitalized patients and mortality differed significantly between men and women, particularly among the 45- to 55- and 65- to 74-year-old age groups, with a smaller decrease observed in women.
Among men, a slight decrease in patients hospitalized for HF and a substantial reduction in mortality were observed. Among women, only a large decrease in HF mortality was observed. HF remains one of the leading causes of death and hospitalization in France, particularly in the elderly.
本研究旨在描述 2000 年至 2012 年期间法国因心力衰竭(HF)住院患者的年度趋势和 HF 相关死亡率。
从法国国家住院数据库(PMSI)中提取住院数据。死亡率数据来自法国国家死亡率数据库。选择构成死亡根本原因或相关原因的 HF 事件。使用 2010 年欧洲人口普查人口作为标准人口对死亡率进行年龄标准化。使用泊松回归模型检验时间趋势。2012 年,因 HF 住院患者的总体年龄标准化率为每 10 万人 246.2 例。2010 年,HF 相关死亡率的年龄标准化率为每 10 万人 113.8 例。2002 年至 2012 年期间,住院患者率保持稳定,而 2000 年至 2010 年期间,死亡率每年下降 3.3%。男性和女性的住院患者和死亡率趋势差异显著,尤其是在 45 至 55 岁和 65 至 74 岁年龄组中,女性的下降幅度较小。
在男性中,因 HF 住院的患者略有减少,死亡率大幅下降。在女性中,仅观察到 HF 死亡率的大幅下降。HF 仍然是法国导致死亡和住院的主要原因之一,尤其是在老年人中。