多囊肾病研究的未来——12位卡普兰奖获得者眼中的未来
The Future of Polycystic Kidney Disease Research--As Seen By the 12 Kaplan Awardees.
作者信息
Antignac Corinne, Calvet James P, Germino Gregory G, Grantham Jared J, Guay-Woodford Lisa M, Harris Peter C, Hildebrandt Friedhelm, Peters Dorien J M, Somlo Stefan, Torres Vicente E, Walz Gerd, Zhou Jing, Yu Alan S L
机构信息
National Institute of Health and Medical Research, Laboratory of Inherited Kidney Diseases, Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, and The Department of Genetics, Necker Hospital, Paris, France;
The Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas;
出版信息
J Am Soc Nephrol. 2015 Sep;26(9):2081-95. doi: 10.1681/ASN.2014121192. Epub 2015 May 7.
Polycystic kidney disease (PKD) is one of the most common life-threatening genetic diseases. Jared J. Grantham, M.D., has done more than any other individual to promote PKD research around the world. However, despite decades of investigation there is still no approved therapy for PKD in the United States. In May 2014, the University of Kansas Medical Center hosted a symposium in Kansas City honoring the occasion of Dr. Grantham's retirement and invited all the awardees of the Lillian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease to participate in a forward-thinking and interactive forum focused on future directions and innovations in PKD research. This article summarizes the contributions of the 12 Kaplan awardees and their vision for the future of PKD research.
多囊肾病（PKD）是最常见的危及生命的遗传性疾病之一。医学博士贾里德·J·格兰瑟姆在推动全球PKD研究方面所做的工作比其他任何人都多。然而，尽管经过了数十年的研究，美国仍没有获批用于治疗PKD的疗法。2014年5月，堪萨斯大学医学中心在堪萨斯城举办了一场研讨会，以纪念格兰瑟姆博士退休，并邀请了所有获得莉莲·简·卡普兰多囊肾病认识进展国际奖的获奖者参加一个具有前瞻性和互动性的论坛，该论坛聚焦于PKD研究的未来方向和创新。本文总结了12位卡普兰奖获得者的贡献以及他们对PKD研究未来的展望。
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