Hahn R G
Research Unit, Södertälje Hospital and Department of Anesthesiology, Linköping University, Linköping, Sweden.
Acta Anaesthesiol Scand. 2015 Oct;59(9):1081-93. doi: 10.1111/aas.12550. Epub 2015 May 8.
Fluid absorption is a well-known complication of endoscopic surgeries, such as transurethral prostatic resection and transcervical endometrial resection. Absorption of electrolyte-free fluid in excess of 1 L, which occurs in 5% to 10% of the operations, markedly increases the risk of adverse effects from the cardiovascular and neurological systems. Absorption of isotonic saline, which is used with the new bipolar resection technique, will change the scenario of adverse effects in a yet unknown way. Hyponatremia no longer occurs, but marking the saline with ethanol reveals that fluid absorption occurs just as much as with monopolar prostate resections.
Ethanol monitoring is a method for non-invasive indication and quantification of fluid absorption that has been well evaluated. By using an irrigating fluid that contains 1% of ethanol, updated information about fluid absorption can be obtained at any time perioperatively by letting the patient breathe into a hand-held alcolmeter.
Regression equations and nomograms with variable complexity are available for estimating how much fluid has been absorbed, both when the alcolmeter is calibrated to show the blood ethanol level and when it is calibrated to show the breath ethanol concentration. Examples of how such estimations should be performed are given in this review article.
The difficulty is that the anesthesiologist must be aware of how the alcolmeter is calibrated (for blood or breath) and be able to distinguish between the intravascular and extravascular absorption routes, which give rise to different patterns and levels of breath ethanol concentrations.
液体吸收是经尿道前列腺切除术和经宫颈子宫内膜切除术等内镜手术中一种众所周知的并发症。无电解质液体吸收超过1升,这种情况在5%至10%的手术中会出现,会显著增加心血管和神经系统出现不良反应的风险。与新型双极切除术技术一起使用的等渗盐水的吸收,将以一种尚不清楚的方式改变不良反应的情况。低钠血症不再发生,但用乙醇标记盐水后发现,液体吸收情况与单极前列腺切除术时一样。
乙醇监测是一种用于液体吸收的非侵入性指示和定量的方法,已经得到了充分评估。通过使用含有1%乙醇的冲洗液,在围手术期的任何时候,让患者对着手持式酒精检测仪呼气,就可以获得有关液体吸收的最新信息。
当酒精检测仪校准以显示血液乙醇水平以及校准以显示呼气乙醇浓度时,都有复杂度不同的回归方程和列线图可用于估计吸收了多少液体。这篇综述文章给出了进行此类估计的示例。
困难在于麻醉医生必须知道酒精检测仪是如何校准的(针对血液还是呼气),并且能够区分血管内和血管外的吸收途径,这两种途径会产生不同模式和水平的呼气乙醇浓度。