Carter Barry L, Levy Barcey T, Gryzlak Brian, Chrischilles Elizabeth A, Vander Weg Mark W, Christensen Alan J, James Paul A, Moss Carol A, Parker Christopher P, Gums Tyler, Finkelstein Rachel J, Xu Yinghui, Dawson Jeffrey D, Polgreen Linnea A
Department of Pharmacy Practice and Science, College of Pharmacy, United States; Department of Family Medicine, Roy J. and Lucille A. Carver College of Medicine, United States.
Department of Family Medicine, Roy J. and Lucille A. Carver College of Medicine, United States.
Contemp Clin Trials. 2015 Jul;43:25-32. doi: 10.1016/j.cct.2015.04.014. Epub 2015 May 4.
Many large health systems now employ clinical pharmacists in team-based care to assist patients and physicians with management of cardiovascular (CV) diseases. However, small private offices often lack the resources to hire a clinical pharmacist for their office. The purpose of this study is to evaluate whether a centralized, web-based CV risk service (CVRS) managed by clinical pharmacists will improve guideline adherence in primary care medical offices in rural and small communities.
This study is a cluster randomized prospective trial in 12 primary care offices. Medical offices were randomized to either the CVRS intervention or usual care. The intervention will last for 12 months and all subjects will have research visits at baseline and 12 months. Primary outcomes will include adherence to treatment guidelines and control of key CV risk factors. Data will also be abstracted from the medical record at 30 months to determine if the intervention effect is sustained after it is discontinued.
This study will enroll subjects through 2015 and results will be available in 2018. This study will provide information on whether a distant, centralized CV risk service can improve guideline adherence in medical offices that lack the resources to employ clinical pharmacists.
许多大型医疗系统现在在团队式医疗中聘用临床药剂师，以协助患者和医生管理心血管疾病。然而，小型私人诊所往往缺乏资源为其办公室聘请临床药剂师。本研究的目的是评估由临床药剂师管理的集中式网络心血管风险服务（CVRS）是否会提高农村和小社区基层医疗办公室对指南的依从性。
本研究是一项在12个基层医疗办公室进行的整群随机前瞻性试验。医疗办公室被随机分为CVRS干预组或常规治疗组。干预将持续12个月，所有受试者将在基线和12个月时进行研究访视。主要结局将包括对治疗指南的依从性和关键心血管危险因素的控制。还将在30个月时从病历中提取数据，以确定干预效果在停止后是否持续。
本研究将在2015年之前招募受试者，结果将于2018年公布。本研究将提供关于远程集中式心血管风险服务是否能提高缺乏资源聘用临床药剂师的医疗办公室对指南依从性的信息。
