Rosell-Camps Antonio, Riera-Llodrá Joana María, Colom-Segui Marina, Zibetti Sara, Amengual-Antich Isabel
Rev Esp Enferm Dig. 2015 May;107(5):313-5.
Collagenous gastritis (CG) is an uncommon condition known in the pediatric age. It is characterized by the presence of subepithelial collagen bands (> 10 microm) associated with lymphoplasmacytic infiltration of the stomach's lamina propria. Symptoms manifested by patients with CG may be common with many other disorders. It typically manifests with epigastralgia, vomiting, and iron deficiency during pre-adolescence. This condition's pathophysiology remains unclear. In contrast to adults, where association with collagenous colitis and other autoimmune conditions is more common, pediatric involvement is usually confined to the stomach. Drugs of choice include proton pump inhibitors and corticoids. A case is reported of a 12-year-old girl with abdominal pain and ferritin deficiency who was diagnosed with CG based on gastric biopsy and experienced a favorable outcome.
胶原性胃炎(CG)是一种在儿童期较为罕见的疾病。其特征是存在上皮下胶原带(>10微米),伴有胃固有层的淋巴细胞和浆细胞浸润。CG患者表现出的症状可能与许多其他疾病相同。它通常在青春期前表现为上腹部疼痛、呕吐和缺铁。这种疾病的病理生理学仍不清楚。与成年人不同,成年人中与胶原性结肠炎和其他自身免疫性疾病的关联更为常见,而儿童受累通常局限于胃部。首选药物包括质子泵抑制剂和皮质类固醇。本文报告了一例12岁腹痛且铁蛋白缺乏的女孩,经胃活检诊断为CG,并获得了良好的治疗效果。