de Lima Mário Maciel, de Lima Mário Maciel, Granja Fabiana
Department of Urology, Coronel Mota Hospital, Rua Levindo Inácio de Oliveira, 1547, Paraviana, Boa Vista, RR, CEP: 69307-272, Brazil.
Biodiversity Research Center, Federal University of Roraima (CBio/UFRR), Boa Vista, Brazil.
BMC Urol. 2015 May 8;15:39. doi: 10.1186/s12894-015-0033-6.
Genital warts caused by human papillomavirus (HPV) infection are the most common sexually transmitted disease leading to anogential lesions. Although the laser therapy has been shown to be effective in a number of conditions, the use of laser diode vaporization in urological applications and the understanding on its effectiveness as a treatment for various urological conditions is limited. Therefore, the aim of this study was to evaluate the efficacy of diode laser vaporization as a treatment for genital lesions.
Patients presenting with genital lesions at the urology outpatient clinic at Coronel Mota Hospital, between March 2008 and October 2014, were enrolled into the study. Data collected included age, gender, duration of the lesion, site of the lesion and numbers of the lesions, length of follow-up, recurrence of lesions after treatment and whether there were any complications.
A total of 92 patients were enrolled in the study; 92.4% (n = 85) male; mean age (± SD) 27.92 ± 8.272 years. The patients presented with a total of 296 lesions, with a median of 3 lesions each, including penis (n = 78), urethra (n = 4) lesions, and scrotum (n = 2) lesions. Lesions ranged in size from 0.1 to 0.5 cm(2), most commonly 0.3 cm(2) (n = 38; 41.3%), 0.4 cm(2) (n = 21; 22.8%) or 0.5 cm(2) (n = 20; 21.7%). Patients most commonly reported that they had their lesions for a duration of 12 (n = 29; 31.5%) or 6 months (n = 23; 25.0%). Eighteen patients (19.6%) had a recurrence after their 1(st)/conventional treatment. There were no incidences of post-operative infection or complications from the laser diode vaporization.
Laser diode vaporization can be considered as an alternative method for treating genital lesions in urology, with satisfactory results in terms of pain, aesthetic and minimal recurrence.
人乳头瘤病毒(HPV)感染引起的尖锐湿疣是导致肛门生殖器病变的最常见性传播疾病。尽管激光疗法在许多情况下已被证明有效,但激光二极管汽化在泌尿外科应用中的使用及其作为各种泌尿外科疾病治疗方法的有效性的认识有限。因此,本研究的目的是评估二极管激光汽化治疗生殖器病变的疗效。
2008年3月至2014年10月期间在科罗内尔·莫塔医院泌尿外科门诊出现生殖器病变的患者被纳入研究。收集的数据包括年龄、性别、病变持续时间、病变部位、病变数量、随访时间、治疗后病变复发情况以及是否有任何并发症。
共有92例患者纳入研究;92.4%(n = 85)为男性;平均年龄(±标准差)27.92 ± 8.272岁。患者共有296个病变,中位数为每个患者3个病变,包括阴茎(n = 78)、尿道(n = 4)病变和阴囊(n = 2)病变。病变大小从0.1至0.5 cm²不等,最常见的是0.3 cm²(n = 38;41.3%)、0.4 cm²(n = 21;22.8%)或0.5 cm²(n = 20;21.7%)。患者最常报告病变持续时间为12个月(n = 29;31.5%)或6个月(n = 23;25.0%)。18例患者(19.6%)在首次/常规治疗后复发。激光二极管汽化术后无感染或并发症发生。
激光二极管汽化可被视为泌尿外科治疗生殖器病变的一种替代方法,在疼痛、美观和最小复发方面取得了满意的效果。