Laser Division, The Dermatology Centre, Salford Royal Hospitals Foundation Trust, Salford, UK.
Br J Dermatol. 2009 Oct;161(4):814-8. doi: 10.1111/j.1365-2133.2009.09317.x. Epub 2009 Jul 14.
Rhinophyma is a progressive, localized or generalized nasal deformity resulting from hypertrophy of sebaceous and connective tissue. The CO(2) laser has been used for treatment of rhinophyma, but the long-term efficacy of the treatment is unknown.
To review the outcome of 124 patients with rhinophyma treated with the CO(2) laser between 1996 and 2008 in our centre.
Exuberant sebaceous tissue was ablated using the Sharplan 40C CO(2) laser (Sharplan Lasers UK Ltd, London, U.K.) under local anaesthesia. The technique varied with the severity of rhinophyma; the laser was used in a continuous mode to debulk the larger rhinophymas, and in a resurfacing mode (Silk Touch scanner; Sharplan, 4-7-mm spot at 20-40 W) or continuous mode (10-20 W using a defocused 2-3-mm beam) to reshape the nasal contours. Outcomes were determined by case notes, clinical review and questionnaire.
Laser treatment was completed in a single session in 115 of 124 patients. All patients were reviewed 3 months post-treatment. Results were classified as good to excellent in 118 and poor in six patients. All patients were sent a satisfaction questionnaire in 2008 and 52 patients replied. Patients reported high levels of satisfaction following treatment. The post-treatment response at 3-month review was maintained long term. The main complications were pain associated with injection of local anaesthetic, scarring and hypopigmentation (four patients) and open pores (two patients).
The CO(2) laser is an effective and durable treatment for rhinophyma. Treatment carries a low risk of side-effects and is associated with high patient acceptability and satisfaction.
酒渣鼻是一种进行性的、局部或全身性的鼻部畸形,是由皮脂腺和结缔组织的肥大引起的。CO2 激光已被用于酒渣鼻的治疗,但长期疗效尚不清楚。
回顾我们中心在 1996 年至 2008 年间使用 CO2 激光治疗 124 例酒渣鼻患者的结果。
在局部麻醉下,使用 Sharplan 40C CO2 激光(Sharplan Lasers UK Ltd,伦敦,英国)切除过多的皮脂腺组织。根据酒渣鼻的严重程度,采用不同的技术;较大的酒渣鼻采用连续模式进行去脂,较小的酒渣鼻采用表面重塑模式(Silk Touch 扫描仪;Sharplan,20-40 W,4-7mm 光斑)或连续模式(10-20 W,使用 2-3mm 聚焦光束)进行重塑鼻轮廓。通过病历、临床检查和问卷调查来确定治疗结果。
124 例患者中有 115 例在一次治疗中完成了激光治疗。所有患者均在治疗后 3 个月进行了随访。结果分为 118 例良好至优秀和 6 例差。2008 年,所有患者均收到满意度调查问卷,52 例患者进行了回复。治疗后患者满意度高。3 个月随访时的治疗反应长期维持。主要并发症包括局部麻醉注射相关疼痛、瘢痕形成和色素减退(4 例)和毛孔粗大(2 例)。
CO2 激光是酒渣鼻的一种有效且持久的治疗方法。治疗的副作用风险低,患者接受度和满意度高。