Pizzol Damiano, Putoto Giovanni, Chhaganlal Kajal D
Operative Research Unit, Doctors with Africa CUAMM, Rua Fernao Mendes Pinto 165, Ponta Gea, 1363 Beira, Mozambique ; Center for Research in Infectious Diseases, Faculty of Health Sciences, Catholic University of Mozambique, Beira, Mozambique.
Operative Research Unit, Doctors with Africa CUAMM, Padua, Italy ; Center for Research in Infectious Diseases, Faculty of Health Sciences, Catholic University of Mozambique, Beira, Mozambique.
Virusdisease. 2016 Jun;27(2):116-22. doi: 10.1007/s13337-016-0319-7. Epub 2016 May 3.
Human Papillomavirus is agent of the most common sexually transmitted disease which is able to infect mucosal and cutaneous membranes of the anogenital region, upper aerodigestive tract, and other head and neck mucosal regions. Although mainly HPV infection can be asymptomatic and transient, it may persist and give rise to various lesions such as warts, condyloma dysplasia and cancers depending on low or high risk type of HPV infection. Moreover, growing recent evidence suggests a role of this virus in male and female fertility. To date no effective prevention, test, treatment and control strategies are provided for people in developing countries despite the reported high incidence of HPV both in women and men. This paper reviews the more recent literature about HPV infection highlighting epidemiology, related pathologies and possible fertility effects of HPV in male and female with particular attention to the Mozambique context.
人乳头瘤病毒是最常见的性传播疾病的病原体，能够感染肛门生殖器区域、上呼吸道消化道以及其他头颈部黏膜区域的黏膜和皮肤。虽然人乳头瘤病毒感染主要可能无症状且为一过性，但根据低风险或高风险的人乳头瘤病毒感染类型，它可能持续存在并引发各种病变，如疣、发育异常的湿疣和癌症。此外，最近越来越多的证据表明这种病毒在男性和女性生育方面发挥作用。尽管据报道人乳头瘤病毒在女性和男性中的发病率都很高，但迄今为止，发展中国家的人们尚未获得有效的预防、检测、治疗和控制策略。本文回顾了关于人乳头瘤病毒感染的最新文献，重点介绍了其流行病学、相关病理学以及人乳头瘤病毒对男性和女性生育可能产生的影响，并特别关注莫桑比克的情况。
