Shpilberg O, Ehrenfeld M, Berkovitz M, Maier M K, Samra Y
Department of Medicine C, Chaim Sheba Medical Center, Tel Hashomer, Israel.
South Med J. 1989 Dec;82(12):1552-4. doi: 10.1097/00007611-198912000-00023.
We have described an 82-year-old man with HCL who had autoimmune manifestations, paraproteinemia, and cryoglobulinemia. Chemotherapy resulted in a dramatic response, with a decrease in the tumor mass, a reduction in the clinical and serologic features of the autoimmune syndrome, and disappearance of the cryoglobulin, but without a significant change in the serum level of paraprotein.
我们描述了一名82岁患有毛细胞白血病（HCL）的男性，他有自身免疫表现、副蛋白血症和冷球蛋白血症。化疗产生了显著反应，肿瘤肿块减小，自身免疫综合征的临床和血清学特征减轻，冷球蛋白消失，但副蛋白的血清水平没有明显变化。
