育龄期农村妇女有症状白带的微生物学特征分析的效用

Utility of microbiological profile of symptomatic vaginal discharge in rural women of reproductive age group.

作者信息

Masand Deepa Lokwani, Patel Jaya, Gupta Sweta

机构信息

Associate Professor, Department of Obstetrics and Gynaecology, National Institute of Medical Sciences , Shobhanagar Jaipur (Rajasthan), India .

Student, Department of Obstetrics and Gynaecology, National Institute of Medical Sciences , Shobhanagar Jaipur (Rajasthan), India .

出版信息

J Clin Diagn Res. 2015 Mar;9(3):QC04-7. doi: 10.7860/JCDR/2015/12161.5623. Epub 2015 Mar 1.

DOI:10.7860/JCDR/2015/12161.5623

PMID:25954668

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4413118/

Abstract

INTRODUCTION

Symptomatic vaginal discharge is the most frequent symptom in women of reproductive age group. Owing to social stigma majority of affected women hesitate to seek medical consultation. Therefore the actual incidence of vaginal discharge is much more than what is reported. The aim of the study is to determine the microbiological profile of symptomatic vaginal discharge in rural area and its utility in the management of genital tract infection.

MATERIALS AND METHODS

This was a descriptive type of observational study, conducted in sexually active women of reproductive age group (18-45 years) attending the OPD/IPD of Obstetrics and Gynaecology Department of National Institute of Medical Sciences, Shobhanagar, Jaipur (Rajasthan), over a period of 18 months from June 2012 to December 2013. Hundred sexually active non pregnant women of reproductive age group (18-45 years) were included in the study. After taking consent general physical examination along with pelvic examination was performed. Two high vaginal swabs and blood sample were collected for various tests. Hanging drop preparation was immediately made. This was followed by gram staining and culture. Chlamydia trachomatis IgM antibody was detected by ELISA method.

RESULTS

Out of 100 women with symptomatic vaginal discharge, specific diagnosis was obtained in 89% of cases whereas no specific aetiology was found in 11% cases. Mean age was 32.60 years. Fifty-three percent patient had Bacterial vaginosis, candidiasis was found in 14% cases, 16% had Chlamydia trachomatis infection while Trichomonas vaginalis infection was detected in 6% cases. Homogenous discharge was most prevalent (52%), followed by mucopurulant discharge in 23% of women.

CONCLUSION

Patient with symptomatic vaginal discharge need to be actively managed with appropriate antimicrobial agents. Judicious management may be helpful in prevention of HIV, HPV, CIN and post infection sequelae.

摘要

引言

有症状的阴道分泌物是育龄期女性最常见的症状。由于社会 stigma，大多数受影响的女性不愿寻求医疗咨询。因此，阴道分泌物的实际发病率远高于报告的发病率。本研究的目的是确定农村地区有症状阴道分泌物的微生物学特征及其在生殖道感染管理中的作用。

材料与方法

这是一项描述性观察性研究，在 2012 年 6 月至 2013 年 12 个月的 18 个月期间，对在斋浦尔（拉贾斯坦邦）Shobhanagar 的国家医学科学研究所妇产科门诊/住院部就诊的育龄期（18 - 45 岁）性活跃女性进行。本研究纳入了 100 名育龄期（18 - 45 岁）性活跃非孕妇。在获得同意后，进行了全身检查以及盆腔检查。采集了两份高阴道拭子和血液样本进行各种检测。立即制作悬滴标本。随后进行革兰氏染色和培养。采用 ELISA 法检测沙眼衣原体 IgM 抗体。

结果

在 100 名有症状阴道分泌物的女性中，89%的病例获得了明确诊断，而 11%的病例未发现明确病因。平均年龄为 32.60 岁。53%的患者患有细菌性阴道病，14%的病例发现念珠菌病，16%的患者感染沙眼衣原体，6%的病例检测到滴虫性阴道炎。均质分泌物最为常见（52%），其次是 23%的女性出现黏液脓性分泌物。