Kubyshkin V F, Mazurets A F, Rozenberg V D, Gorelov K P, Perfil'eva I G
Ter Arkh. 1989;61(9):82-5.
Disorders of heart rhythm and conduction were characterized clinically and by electrocardiography in 82 patients with dilated and hypertrophic cardiomyopathies. Based on an analysis of blood lymphocyte cytochemistry energy-deficient conditions of the myocardium were identified in the patients examined. In order to correct the metabolic shifts in the myocardium, use was made of a coenzymic medicamentous complex including pyridoxalphosphate, cobamamide and phosphadene. The complex indicated was shown to potentiate the action of antiarrhythmic agents employed in the treatment of idiopathic cardiomyopathies.
对82例扩张型和肥厚型心肌病患者的心律失常和传导障碍进行了临床及心电图特征分析。通过对血淋巴细胞细胞化学分析，确定了所检查患者心肌的能量缺乏状况。为纠正心肌代谢变化，使用了一种包含磷酸吡哆醛、钴胺酰胺和磷酸腺苷的辅酶药物复合物。结果表明，该复合物可增强用于治疗特发性心肌病的抗心律失常药物的作用。
