严重高甘油三酯血症继发的多神经根病
Polyradiculopathy secondary to severe hypertriglyceridemia.
作者信息
Nesbitt Cassie, Wong Daniel, Batchelor Peter
机构信息
Department of Neurology, Barwon Health, Barwon Heads, Victoria, Australia.
Department of Neurology, Barwon Health, Geelong, Victoria, Australia.
出版信息
BMJ Case Rep. 2015 May 8;2015:bcr2014206966. doi: 10.1136/bcr-2014-206966.
Abstract
A 74-year-old man presented with a subacute severe thoracic polyradiculopathy affecting the T4-T8 dermatomes bilaterally. Extensive investigation demonstrated markedly raised triglyceride levels of 44 mmol/L (<1.7). The patient's unique presentation is discussed alongside a review of triglyceride-induced neurotoxicity and therapeutic management.
摘要
一名74岁男性患者出现亚急性严重胸段多发性神经根病，双侧累及T4 - T8皮节。广泛检查显示甘油三酯水平显著升高至44 mmol/L（正常范围<1.7 mmol/L）。本文在回顾甘油三酯诱导的神经毒性及治疗管理的同时，对该患者的独特表现进行了讨论。
相似文献
1
Polyradiculopathy secondary to severe hypertriglyceridemia.严重高甘油三酯血症继发的多神经根病
BMJ Case Rep. 2015 May 8;2015:bcr2014206966. doi: 10.1136/bcr-2014-206966.
2
Determining triglyceride reductions needed for clinical impact in severe hypertriglyceridemia.确定严重高甘油三酯血症中临床影响所需的甘油三酯降低水平。
Am J Med. 2014 Jan;127(1):36-44.e1. doi: 10.1016/j.amjmed.2013.09.018. Epub 2013 Oct 8.
3
Elevated Triglyceride Level Is Independently Associated With Increased All-Cause Mortality in Patients With Established Coronary Heart Disease: Twenty-Two-Year Follow-Up of the Bezafibrate Infarction Prevention Study and Registry.甘油三酯水平升高与已确诊冠心病患者的全因死亡率增加独立相关：苯扎贝特预防心肌梗死研究及注册登记的22年随访
Circ Cardiovasc Qual Outcomes. 2016 Mar;9(2):100-8. doi: 10.1161/CIRCOUTCOMES.115.002104. Epub 2016 Mar 8.
4
Pathogenesis of CHD: the role of elevated triglycerides.
J Am Acad Nurse Pract. 2007;19(12 Suppl 2):4-6, 13-4.
5
6
Novel CREB3L3 Nonsense Mutation in a Family With Dominant Hypertriglyceridemia.家族性单纯性高甘油三酯血症中新型 CREB3L3 无义突变。
Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2694-9. doi: 10.1161/ATVBAHA.115.306170. Epub 2015 Oct 1.
7
White, opaque fluid in a blood draw. Hypertriglyceridemia.采血时出现白色不透明液体。高甘油三酯血症。
Am Fam Physician. 2009 Apr 15;79(8):699-700.
8
Hypertriglyceridaemia unresponsive to multiple treatments.对多种治疗无反应的高甘油三酯血症。
BMJ Case Rep. 2015 Oct 14;2015:bcr2015210788. doi: 10.1136/bcr-2015-210788.
9
Impact of hypertriglyceridemia on the outcome of acute biliary pancreatitis.高甘油三酯血症对急性胆源性胰腺炎预后的影响。
Am J Med Sci. 2014 Nov;348(5):399-402. doi: 10.1097/MAJ.0000000000000333.
10
Clinical and economic benefits observed when follow-up triglyceride levels are less than 500 mg/dL in patients with severe hypertriglyceridemia.在严重高甘油三酯血症患者中，当随访时的甘油三酯水平低于 500mg/dL 时观察到的临床和经济效益。
J Clin Lipidol. 2012 Sep-Oct;6(5):450-61. doi: 10.1016/j.jacl.2012.08.007. Epub 2012 Aug 30.
引用本文的文献
1
Current Diagnosis and Treatment of Painful Small Fiber Neuropathy.疼痛性小纤维神经病的当前诊断与治疗。
Curr Neurol Neurosci Rep. 2019 Nov 26;19(12):103. doi: 10.1007/s11910-019-1020-1.
本文引用的文献
1
Hyperlipidemia: a new therapeutic target for diabetic neuropathy.高脂血症：糖尿病周围神经病变的新治疗靶点。
J Peripher Nerv Syst. 2009 Dec;14(4):257-67. doi: 10.1111/j.1529-8027.2009.00237.x.
2
A case of severe neuropathy associated with hypertriglyceridemia.
Endocr Pract. 2008 Nov;14(8):1020-2. doi: 10.4158/EP.14.8.1020.
3
Hypertriglyceridemia and peripheral neuropathy in neurologically asymptomatic patients.神经无症状患者的高甘油三酯血症和周围神经病变
Neuro Endocrinol Lett. 2005 Dec;26(6):775-9.
4
The effects of intensive glycemic control on neuropathy in the VA cooperative study on type II diabetes mellitus (VA CSDM).在退伍军人事务部II型糖尿病合作研究（VA CSDM）中强化血糖控制对神经病变的影响。
J Diabetes Complications. 1999 Sep-Dec;13(5-6):307-13. doi: 10.1016/s1056-8727(99)00062-8.
5
Neuropathy associated with hyperlipidemia.与高脂血症相关的神经病变。
Neurology. 1994 Nov;44(11):2185-6. doi: 10.1212/wnl.44.11.2185.
6
Microangiopathy in human diabetic neuropathy.人类糖尿病性神经病变中的微血管病变
Acta Neuropathol. 1985;68(4):295-305. doi: 10.1007/BF00690832.
Zotero 插件