严重呼吸道合胞病毒细支气管炎中的HLA I类抗原
HLA class I antigens in severe RSV bronchiolitis.
作者信息
Isaacs D, Taylor C J, Ting A, McMichael A J
机构信息
Department of Paediatrics, John Radcliffe Hospital, Oxford, U.K.
出版信息
Tissue Antigens. 1989 Sep;34(3):210-2. doi: 10.1111/j.1399-0039.1989.tb01740.x.
Abstract
Cytotoxic T-lymphocytes (CTL) recognize virus-infected cells in association with HLA class I antigens. There is strong evidence of the importance of CTL in respiratory syncytial virus (RSV) infections. We looked for but were unable to demonstrate an association between particular HLA class I antigens and severe RSV bronchiolitis in infants.
摘要
细胞毒性T淋巴细胞（CTL）通过与I类人类白细胞抗原（HLA）结合来识别病毒感染细胞。有充分证据表明CTL在呼吸道合胞病毒（RSV）感染中具有重要作用。我们进行了研究，但未能证实特定的I类HLA抗原与婴儿严重RSV细支气管炎之间存在关联。
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