Knepper L E, Biller J, Tranel D, Adams H P, Marsh E E
Division of Cerebrovascular Disease, University of Iowa College of Medicine, Iowa City.
Stroke. 1989 Dec;20(12):1730-2. doi: 10.1161/01.str.20.12.1730.
We reviewed 49 patients with Wernicke's aphasia resulting from a stroke. Their aphasia was classified on the basis of comprehensive neuropsychological testing. Wernicke's aphasia was more common in older patients and in men. Cerebral infarction occurred in 38 patients (78%) and intracerebral hemorrhage in seven (14%); the remaining four patients (8%) developed aphasia after surgery for aneurysmal subarachnoid hemorrhage. Embolic events were the most common etiology of Wernicke's aphasia in the 38 patients with cerebral infarction, with cardiac emboli in 40% and large-vessel atheroemboli from a carotid source in 16%. In patients with Wernicke's aphasia secondary to infarction, an embolic source should be sought. Patients with Wernicke's aphasia should have computed tomography to exclude intracerebral hemorrhage before institution of anticoagulant therapy.
我们回顾了49例因中风导致韦尼克失语症的患者。他们的失语症是根据全面的神经心理学测试进行分类的。韦尼克失语症在老年患者和男性中更为常见。38例患者（78%）发生脑梗死，7例（14%）发生脑出血；其余4例患者（8%）在动脉瘤性蛛网膜下腔出血手术后出现失语症。在38例脑梗死患者中，栓塞事件是韦尼克失语症最常见的病因，40%为心脏栓子，16%为来自颈动脉源的大血管动脉粥样硬化栓子。对于继发于梗死的韦尼克失语症患者，应寻找栓塞源。韦尼克失语症患者在开始抗凝治疗前应进行计算机断层扫描以排除脑出血。
