Bulyakova N V, Azarova V S
Morfologiia. 2015;147(1):26-35.
Histological, cytological and morphometric changes in the thymus of 1 month-old, adult (3-4 months-old) and old (24-30 months-old) rats (24 animals in each group) were studied during muscle regeneration after the alloplasty of the injured area with the muscle tissue from the animal of the same age. Muscles of the donor or recipient were subjected to the course of preliminary irradiation with He-Ne laser (dose: 4.5-5.4 J/cm2 for each extremity; total dose of 9.0-10.8 J/cm2 per animal). It was shown that the exposure of gastrocnemius muscles that were prepared for the operation to He-Ne laser radiation decreased morpho-functional activity of the thymus in young, adult and old recipient rats the before surgery. This was demonstrated by its weaker reaction to the allograft during the early time intervals after surgery. The observed effect was more pronounced with the increasing age of an animal.
研究了1月龄、成年（3 - 4月龄）和老年（24 - 30月龄）大鼠（每组24只动物）在使用同年龄动物的肌肉组织对损伤区域进行同种异体成形术后肌肉再生过程中胸腺的组织学、细胞学和形态计量学变化。供体或受体的肌肉接受了氦氖激光的预处理（剂量：每个肢体4.5 - 5.4 J/cm²；每只动物的总剂量为9.0 - 10.8 J/cm²）。结果表明，术前对准备手术的腓肠肌进行氦氖激光照射会降低年轻、成年和老年受体大鼠胸腺的形态功能活性。这在术后早期对同种异体移植的反应较弱中得到了证明。随着动物年龄的增加，观察到的效果更加明显。
