Compston P C, Turner T, Wylie C E, Payne R J
Rossdales Equine Hospital, Newmarket, Suffolk, UK.
Royal (Dick) School of Veterinary Studies, Easter Bush Veterinary Centre, Edinburgh, UK.
Equine Vet J. 2016 Jul;48(4):451-6. doi: 10.1111/evj.12456. Epub 2015 Jul 31.
Laser resection for the treatment of sarcoids is an established part of equine practice; however, few studies have provided long-term follow-up results. Additionally, many previous reports have evaluated several treatments concurrently or have not been able to provide a definitive histological diagnosis of sarcoid.
To establish the success rate following laser resection as a sole treatment for histologically confirmed sarcoids and evaluate risk factors for recurrence.
Retrospective time-to-event analysis.
Horses included had laser surgery to remove at least one sarcoid between 1 July 2005 and 1 September 2012. No previous known/concurrent veterinary treatment was administered. Diagnosis was confirmed by histology in all cases. Clinical data were retrieved from the hospital database. Follow-up information was obtained by telephone questionnaire.
Ninety-nine horses, with a total of 235 sarcoids, were included in the analysis; 82 (83%) had no recurrence of the sarcoid removed and 71 (72%) had no occurrence of any sarcoids following surgery. Horses with sarcoids on the head and neck and those with verrucose sarcoids were at increased risk of recurrence (hazard ratios of 1.61 and 4.03, and 95% confidence intervals of 1.02-2.56 and 1.11-14.7, respectively).
Laser resection of sarcoids in the horse has a positive post operative prognosis. Further work is required to fully evaluate risk factors for recurrence fully.
激光切除治疗马的肉瘤样病变是马医学实践中既定的一部分；然而，很少有研究提供长期随访结果。此外，许多先前的报告同时评估了几种治疗方法，或者无法提供肉瘤样病变的确切组织学诊断。
确定激光切除作为组织学确诊的肉瘤样病变唯一治疗方法后的成功率，并评估复发的危险因素。
回顾性事件发生时间分析。
纳入2005年7月1日至2012年9月1日期间接受激光手术切除至少一个肉瘤样病变的马匹。之前未进行过已知/同期的兽医治疗。所有病例均通过组织学确诊。临床数据从医院数据库中检索。通过电话问卷调查获得随访信息。
分析纳入了99匹马，共235个肉瘤样病变；82个（83%）切除的肉瘤样病变未复发，71个（72%）术后未出现任何肉瘤样病变。头颈部有肉瘤样病变的马和疣状肉瘤样病变的马复发风险增加（风险比分别为1.61和4.03，95%置信区间分别为1.02 - 2.56和1.11 - 14.7）。
马的肉瘤样病变激光切除术后预后良好。需要进一步开展工作以全面评估复发的危险因素。
