Martens A, De Moor A, Vlaminck L, Pille F, Steenhaut M
Department of Surgery and Anaesthesiology of Domestic Animals, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Vet Rec. 2001 Dec 1;149(22):665-9. doi: 10.1136/vr.149.22.665.
Ninety-five horses with sarcoids were subjected to three types of treatment: surgical excision (conventional or carbon dioxide laser), cryotherapy or local BCG vaccination. The type of treatment was selected on the basis of the size, location and clinical appearance of the tumours. The choice between conventional and laser excision was empirical. A successful outcome was obtained in 11 of 14 (79 per cent) of the horses treated by cryosurgery, 18 of 27 (67 per cent) treated by BCG vaccination, 18 of 22 (82 per cent) treated by conventional excision, and 20 of 28 (71 per cent) treated with a carbon dioxide laser. For both excision methods, rigorous measures were taken to avoid autoinoculation and to ensure a wide margin of normal skin. The probability of local recurrence after excision was significantly higher for large sarcoids and sarcoids which had previously failed to respond to treatment. In 10 of the 31 horses with remaining sarcoids, some or all of the untreated sarcoids were observed to regress spontaneously.
95匹患有肉瘤的马接受了三种治疗方法：手术切除（传统手术或二氧化碳激光手术）、冷冻疗法或局部卡介苗接种。治疗方法根据肿瘤的大小、位置和临床表现来选择。传统手术和激光切除之间的选择是凭经验的。冷冻手术治疗的14匹马中有11匹（79%）取得了成功，卡介苗接种治疗的27匹马中有18匹（67%），传统切除治疗的22匹马中有18匹（82%），二氧化碳激光治疗的28匹马中有20匹（71%）。对于两种切除方法，都采取了严格措施以避免自体接种，并确保有宽的正常皮肤边缘。大的肉瘤以及先前对治疗无反应的肉瘤切除后局部复发的可能性明显更高。在31匹仍有肉瘤的马中，有10匹的部分或全部未治疗的肉瘤出现了自发消退。
