Utzinger Linsey M, Mitchell James E, Cao Li, Crosby Ross D, Crow Scott J, Wonderlich Stephen A, Peterson Carol B
Department of Clinical Research, Neuropsychiatric Research Institute, Fargo, North Dakota.
Department of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota.
Int J Eat Disord. 2015 Sep;48(6):785-9. doi: 10.1002/eat.22422. Epub 2015 May 8.
This study examined whether having a history of anorexia nervosa (AN) or bulimia nervosa (BN) is associated with response to treatment in adults with binge eating disorder (BED).
Data from 189 adults diagnosed with BED who were randomly assigned to one of three group cognitive-behavioral (CBT) treatments were analyzed to compare those with and without a history of AN/BN.
A total of 16% of the sample had a history of AN/BN. The BED subgroup with a history of AN/BN presented with higher rates of mood disorders and greater eating-related symptom severity at baseline. Participants with a history of AN/BN also had higher global eating disorder (ED) symptoms at end of treatment (EOT), and more frequent objective binge-eating episodes at EOT and 12-month follow-up.
These findings suggest that in adults with BED, a history of AN/BN is predictive of greater eating-related symptom severity following group-based CBT and poorer short- and long-term binge-eating outcomes. These findings suggest that considering ED history in the treatment of adults with BED may be clinically useful.
本研究探讨神经性厌食症（AN）或神经性贪食症（BN）病史是否与暴食症（BED）成人患者的治疗反应相关。
对189名被诊断为BED的成人患者的数据进行分析，这些患者被随机分配到三种团体认知行为疗法（CBT）治疗组之一，以比较有和没有AN/BN病史的患者。
共有16%的样本有AN/BN病史。有AN/BN病史的BED亚组在基线时出现情绪障碍的比例更高，与饮食相关的症状严重程度更大。有AN/BN病史的参与者在治疗结束时（EOT）的全球饮食失调（ED）症状也更高，在EOT和12个月随访时客观暴食发作更频繁。
这些发现表明，在患有BED的成人中，AN/BN病史预示着基于团体的CBT治疗后与饮食相关的症状严重程度更高，以及短期和长期暴食结果更差。这些发现表明，在治疗患有BED的成人时考虑ED病史可能在临床上有用。
