Shust V F, Markochev A B, Skripkina N S
Vopr Onkol. 1989;35(10):1251-4.
The clinico-morphological data on 99 autopsied cases of Hodgkin's disease were analysed to assess the histological pattern of the disease as a prognostic factor. A correlation between the histologic pattern of the disease and lethality was established for the first 24 months after diagnosis verification. However, transformation of histological pattern was observed in 50% of cases. It is inferred that histological pattern of Hodgkin's disease can be used as a prognostic factor in planning schedule of treatment, changes in the histologic characteristics of pathological process being taken into account.
分析了99例霍奇金病尸检病例的临床形态学数据,以评估该疾病的组织学模式作为预后因素。在确诊后的前24个月,建立了疾病组织学模式与致死率之间的相关性。然而,50%的病例观察到组织学模式的转变。据推断,霍奇金病的组织学模式可作为制定治疗方案时的预后因素,同时要考虑病理过程组织学特征的变化。