全乳放疗期间瘤床加量整合：当前证据综述
Tumor Bed Boost Integration during Whole Breast Radiotherapy: A Review of the Current Evidence.
作者信息
Franco Pierfrancesco, Cante Domenico, Sciacero Piera, Girelli Giuseppe, La Porta Maria Rosa, Ricardi Umberto
机构信息
Department of Oncology, Radiation Oncology, University of Torino, Turin, Italy.
Radiation Oncology Department, Ivrea Community Hospital, ASLTO4, Ivrea, Italy.
出版信息
Breast Care (Basel). 2015 Feb;10(1):44-9. doi: 10.1159/000369845.
Abstract
Radiation therapy delivered with hypofractionation, which involves the delivery of a higher dose per fraction in fewer fractions (generally with a lower total nominal dose) over a shorter overall treatment time, is an established therapeutic option at least for a selected group of early breast cancer patients after breast-conserving surgery. Optimal delivery of the tumor bed boost dose in terms of timing, fractionation, and total dose whenever a hypofractionated schedule is employed has yet to be established. We herein present a review of the current evidence on the role of boost integration in whole breast radiotherapy.
摘要
大分割放疗是指在更短的总治疗时间内，每次分割给予更高剂量（通常总标称剂量较低）、分割次数更少的放疗方式，至少对于保乳手术后特定的早期乳腺癌患者群体而言，这是一种既定的治疗选择。在采用大分割放疗方案时，肿瘤床推量剂量在时间、分割方式和总剂量方面的最佳给予方式尚未确定。我们在此对当前关于推量整合在全乳放疗中作用的证据进行综述。
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