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原发性肾尤因肉瘤/原始神经外胚层肿瘤——诊断难题

Primary Ewing's Sarcoma/Primitive Neuroectodermal Tumor of of Kidney - a Diagnostic Dilemma.

作者信息

Chakrabarti Nirmalya, Dewasi Nikhilesh, Das Snehasish, Bandyopadhyay Arghya, Bhaduri Nandini

机构信息

Department of Pathology, Burdwan Medical College, Burdwan, West Bengal, India.

Department of Pathology, Bankura Sammilani Medical College, Bankura, West Bengal, India.

出版信息

Iran J Cancer Prev. 2015 Mar-Apr;8(2):129-33.

PMID:25960853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4411475/
Abstract

Among the group of small round cell tumors of kidney Ewing's sarcoma/PNET is a very rare entity which has aggressive clinical course. We report a case of renal mass in 24 years old male which was histologically diagnosed as small round cell tumor of kidney. Arrangement of the malignant cell along with vascular network in a filigree pattern was suspicious for a diagnosis of Ewing's sarcoma/PNET which was confirmed by positivity of CD 99 immunohistochemically. Thus careful histological observation and immunohistochemical stains can give the proper diagnosis of primary Ewing's sarcoma/PNET thus removing the diagnostic dilemma in the group of small round cell tumors.

摘要

在肾小圆细胞肿瘤中，尤因肉瘤/原始神经外胚层肿瘤是一种非常罕见的实体瘤，具有侵袭性的临床病程。我们报告一例24岁男性的肾脏肿块，组织学诊断为肾小圆细胞肿瘤。恶性细胞与血管网络呈细丝状排列，怀疑为尤因肉瘤/原始神经外胚层肿瘤，免疫组化CD99阳性证实了这一诊断。因此，仔细的组织学观察和免疫组化染色可以对原发性尤因肉瘤/原始神经外胚层肿瘤做出正确诊断，从而消除小圆细胞肿瘤组中的诊断困境。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/92dba6916410/IJCP-08-129f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/c900ac1adf83/IJCP-08-129f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/a86dd6397e03/IJCP-08-129f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/faf7dc39ccba/IJCP-08-129f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/7019d6907039/IJCP-08-129f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/92dba6916410/IJCP-08-129f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/c900ac1adf83/IJCP-08-129f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/a86dd6397e03/IJCP-08-129f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/faf7dc39ccba/IJCP-08-129f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/7019d6907039/IJCP-08-129f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b276/4411475/92dba6916410/IJCP-08-129f5.jpg

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Ewing sarcoma of the kidney: a rare entity.肾尤因肉瘤：一种罕见的实体瘤。
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