Adler C P, Träger D
Referenzzentrum für Knochentumoren am Pathologischen Institut der Universität Freiburg.
Z Orthop Ihre Grenzgeb. 1989 Sep-Oct;127(5):611-5. doi: 10.1055/s-2008-1040300.
Hemangiopericytomas are very rare tumors that mostly develop in the soft tissues. In rare cases, however, they may occur as primary bone tumors which are extremely rare. In case of such an intraosseous tumor, a bone metastasis of such a soft tissue sarcoma must be considered first and has to be excluded. In a 62 year old female, a hemangiopericytoma of the left femoral neck was diagnosed that had induced a pathological bone fracture. A resection of the femoral head and neck was performed. Anamnestical investigations, however, have shown that 4 years before, such a tumor of the pelvic soft tissues was removed. Thus, the lesion of the femoral neck had to be classified as bone metastasis of a malignant hemangiopericytoma. It has to be emphasized that this special tumor always shows a questionable prognosis and, by histological investigations, it cannot be decided if we are dealing with a benign or malignant tumor growth. Diagnostic managements and clinical problems with hemangiopericytomas are discussed in detail.
血管外皮细胞瘤是非常罕见的肿瘤,大多发生于软组织。然而,在极少数情况下,它们可能作为原发性骨肿瘤出现,这极为罕见。对于这种骨内肿瘤,必须首先考虑并排除这种软组织肉瘤的骨转移。一名62岁女性被诊断出左股骨颈血管外皮细胞瘤,该肿瘤导致了病理性骨折。对股骨头和颈部进行了切除。然而,病史调查显示,4年前曾切除过盆腔软组织的此类肿瘤。因此,股骨颈病变必须归类为恶性血管外皮细胞瘤的骨转移。必须强调的是,这种特殊肿瘤的预后总是难以确定,通过组织学检查,无法判定我们面对的是良性还是恶性肿瘤生长。文中详细讨论了血管外皮细胞瘤的诊断处理和临床问题。