Roggeveen Suzanne, van Os Jim, Lousberg Richel
Department of Psychiatry and Psychology, Maastricht University, Maastricht, Limburg, The Netherlands.
Department of Psychiatry and Psychology, Maastricht University, Maastricht, Limburg, The Netherlands; King's College London, King's Health Partners, Department of Psychosis Studies, Institute of Psychiatry, London, United Kingdom.
PLoS One. 2015 May 11;10(5):e0125390. doi: 10.1371/journal.pone.0125390. eCollection 2015.
This study aimed to investigate whether third generation mobile phone radiation peaks result in event related potentials. Thirty-one healthy females participated. In this single-blind, cross-over design, a 15 minute mobile phone exposure was compared to two 15 minute sham phone conditions, one preceding and one following the exposure condition. Each participant was measured on two separate days, where mobile phone placement was varied between the ear and heart. EEG activity and radiofrequency radiation were recorded jointly. Epochs of 1200 ms, starting 200 ms before and lasting until 1000 ms after the onset of a radiation peak, were extracted from the exposure condition. Control epochs were randomly selected from the two sham phone conditions. The main a-priori hypothesis to be tested concerned an increase of the area in the 240-500 ms post-stimulus interval, in the exposure session with ear-placement. Using multilevel regression analyses the placement*exposure interaction effect was significant for the frontal and central cortical regions, indicating that only in the mobile phone exposure with ear-placement an enlarged cortical reactivity was found. Post-hoc analyses based on visual inspection of the ERPs showed a second significantly increased area between 500-1000 ms post-stimulus for almost every EEG location measured. It was concluded that, when a dialing mobile phone is placed on the ear, its radiation, although unconsciously, is electrically detected by the brain. The question of whether or not this cortical reactivity results in a negative health outcome has to be answered in future longitudinal experiments.
本研究旨在调查第三代移动电话辐射峰值是否会导致事件相关电位。31名健康女性参与了研究。在这项单盲交叉设计中，将15分钟的手机暴露与两种15分钟的假手机条件进行比较，一种在暴露条件之前，一种在暴露条件之后。每位参与者在两个不同的日子进行测量，手机放置位置在耳朵和心脏之间变化。同时记录脑电图活动和射频辐射。从暴露条件中提取在辐射峰值开始前200毫秒开始并持续到辐射峰值开始后1000毫秒的1200毫秒时间段。对照时间段从两种假手机条件中随机选取。要检验的主要先验假设涉及在耳朵放置的暴露阶段，刺激后240 - 500毫秒间隔内面积的增加。使用多水平回归分析，放置*暴露交互效应在额叶和中央皮质区域显著，表明仅在耳朵放置手机的暴露情况下发现皮质反应性增强。基于对事件相关电位的视觉检查的事后分析显示，在几乎每个测量的脑电图位置，刺激后500 - 1000毫秒之间还有第二个显著增加的区域。得出的结论是，当拨号手机放在耳朵上时，其辐射虽然是无意识的，但会被大脑电检测到。这种皮质反应性是否会导致负面健康结果的问题必须在未来的纵向实验中得到解答。
