Hariri Benjamin M, Rhee John S, Garcia Guilherme J M
Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Biotechnology and Bioengineering Center, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
Laryngoscope. 2015 Dec;125(12):2635-41. doi: 10.1002/lary.25367. Epub 2015 May 11.
OBJECTIVES/HYPOTHESIS: (1) To determine objective criteria to predict which patients may benefit most from inferior turbinate reduction surgery. (2) To test whether the site of turbinate reduction, either along the nasal floor (bottom resection) or along the septal side (medial resection), impacts the extent to which nasal resistance is reduced.
Case series.
Three-dimensional reconstructions of the nasal anatomy of five nasal airway obstruction patients were created based on presurgical computed tomography scans. Inferior turbinate reduction models were created for each patient using virtual surgery. Airflow, heat transfer, and humidity transport during inspiration were simulated using computational fluid dynamics (CFD).
Nasal resistance curves revealed little to no difference between bottom resection and medial resection models. In two patients, little change was observed in nasal resistance after virtual inferior turbinate reduction, which was attributed to the narrowest cross-sections being restricted to the anterior nose (i.e., anterior to the inferior turbinate). The three patients whose nasal resistances decreased substantially after virtual inferior turbinate reduction had a narrower airspace in the turbinate region and higher nasal resistance presurgery. Nasal air conditioning capacity was more affected by medial resections.
CFD simulations predicted no significant difference in the decrease in nasal resistance between virtual inferior turbinate reductions performed by bottom versus medial resection of the turbinate. However, bottom resections better preserved the calculated humidification efficiency. The simulations predicted that the greatest reduction in nasal resistance occurs in patients with the highest presurgical resistance in the turbinate region.
目的/假设:(1)确定客观标准,以预测哪些患者可能从下鼻甲缩小手术中获益最大。(2)测试下鼻甲缩小的部位,无论是沿着鼻底(底部切除)还是沿着鼻中隔侧(内侧切除),是否会影响鼻阻力降低的程度。
病例系列。
基于术前计算机断层扫描,创建了5例鼻气道阻塞患者鼻腔解剖结构的三维重建模型。使用虚拟手术为每位患者创建下鼻甲缩小模型。利用计算流体动力学(CFD)模拟吸气过程中的气流、热传递和湿度传输。
鼻阻力曲线显示底部切除模型和内侧切除模型之间几乎没有差异。在两名患者中,虚拟下鼻甲缩小术后鼻阻力几乎没有变化,这归因于最窄横截面局限于前鼻(即下鼻甲前方)。在虚拟下鼻甲缩小术后鼻阻力大幅降低的三名患者中,鼻甲区域的气腔较窄,术前鼻阻力较高。鼻调节能力受内侧切除的影响更大。
CFD模拟预测,下鼻甲底部切除与内侧切除的虚拟下鼻甲缩小术在降低鼻阻力方面无显著差异。然而,底部切除能更好地保留计算出的加湿效率。模拟预测,鼻甲区域术前阻力最高的患者鼻阻力降低最大。
4级。