西班牙巴塞罗那一家儿科医院严重呼吸道疾病的人鼻病毒和肠病毒的分子流行病学。
Molecular epidemiology of severe respiratory disease by human rhinoviruses and enteroviruses at a tertiary paediatric hospital in Barcelona, Spain.
机构信息
Infectious Diseases Research Unit, Department of Paediatrics, Barcelona, Spain.
Paediatric Intensive Care Unit, Hospital Sant Joan de Deu, University of Barcelona, Barcelona, Spain.
出版信息
Clin Microbiol Infect. 2015 Aug;21(8):799.e5-7. doi: 10.1016/j.cmi.2015.04.021. Epub 2015 May 8.
In order to describe the molecular epidemiology of human rhinovirus (HRV) and enterovirus (EV) infection in severely ill children, we studied all episodes of bronchospasm/bronchopneumonia in 6-month-old to 18-year-old patients from January 2010 to May 2012 who required mechanical ventilation. HRV/EVs were detected in 55 (57.3%) of 96 patients, of which 50 (91%) were HRV (HRV-A, 16; HRV-B, 1; HRV-C, 18) and 5 (9%) were EVs (EV-D68, 3). No significant differences in epidemiologic and clinical characteristics were found between different types. In six of the 13 patients who required invasive mechanical ventilation, HRV was the only pathogen detected.
为了描述严重患病儿童中人类鼻病毒（HRV）和肠病毒（EV）感染的分子流行病学，我们研究了 2010 年 1 月至 2012 年 5 月期间需要机械通气的 6 个月至 18 岁患者所有支气管痉挛/支气管肺炎发作。在 96 例患者中的 55 例（57.3%）中检测到 HRV/ EV，其中 50 例（91%）为 HRV（HRV-A，16 例；HRV-B，1 例；HRV-C，18 例），5 例（9%）为 EV（EV-D68，3 例）。不同类型之间在流行病学和临床特征方面无显著差异。在需要有创机械通气的 13 例患者中的 6 例中，HRV 是唯一检测到的病原体。
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