Yawn Barbara P, Bertram Susan, Kurland Marge, Wollan Peter C
Olmsted Medical Center, Department of Research, Rochester, Minnesota
Olmsted Medical Center, Department of Research, Rochester, Minnesota.
Ann Fam Med. 2015 May-Jun;13(3):228-34. doi: 10.1370/afm.1777.
Postpartum depression (PPD) screening at 4 to 12 weeks' postpartum can improve outcomes for women when linked to in-practice management programs. The benefit of repeated PPD screening during the first year postpartum remains unclear.
We report a substudy of a large pragmatic trial of early PPD screening and practice management, the Translating Research into Practice for Postpartum Depression (TRIPPD) study. Outcome analyses were based on demographic information and Patient Health Questionnaire (PHQ-9) screening scores from questionnaires mailed to all enrolled women at baseline (4 to 12 weeks' postpartum) and again at 6 and at 12 months' postpartum. The main outcomes of this substudy were the 6- and 12-month rates of PHQ-9 scores that were 10 or greater for women whose baseline PHQ-9 scores were less than 10. Women whose scores were 10 or greater would be considered at high risk of PPD and appropriate for further evaluation.
At 6 months, 134 (10.9%) of the 1,235 women who did not have PHQ-9 scores greater than 10 at baseline had elevated scores appropriate for further evaluation. At 12 months, 59 (6.1%) of the 969 women who did not have PHQ-9 scores greater than 10 at baseline or at 6 months had elevated scores. Together the 6- and 12-month repeated screenings identified 193 women at high risk of depression. This finding represents 13.5% of the 1,432 women whose screening results were negative for PPD at baseline.
Repeated PPD screening at 6 and 12 months' postpartum increases the percentage of women identified as being at high risk of PPD. Further work will be required to understand the impact of this repeated screening on patient outcomes.
产后4至12周进行产后抑郁症(PPD)筛查,若与实际管理项目相结合,可改善女性的治疗效果。产后第一年重复进行PPD筛查的益处尚不清楚。
我们报告了一项关于早期PPD筛查与实际管理的大型实用试验的子研究,即“将产后抑郁症研究转化为实际应用”(TRIPPD)研究。结果分析基于人口统计学信息以及向所有登记女性在基线时(产后4至12周)、产后6个月和12个月邮寄的问卷中的患者健康问卷(PHQ-9)筛查得分。该子研究的主要结果是,基线PHQ-9得分低于10分的女性在6个月和12个月时PHQ-9得分达到或高于10分的比例。得分达到或高于10分的女性将被视为PPD高危人群,适合进一步评估。
在6个月时,1235名基线时PHQ-9得分未高于10分的女性中有134名(10.9%)得分升高,适合进一步评估。在12个月时,969名在基线或6个月时PHQ-9得分未高于10分的女性中有59名(6.1%)得分升高。6个月和12个月的重复筛查共识别出193名抑郁症高危女性。这一发现占1432名基线时PPD筛查结果为阴性的女性的13.5%。
产后6个月和12个月重复进行PPD筛查可增加被识别为PPD高危女性的比例。需要进一步开展工作来了解这种重复筛查对患者治疗效果的影响。