Department of Obstetrics and Gynecology, Women & Infants Hospital of Rhode Island, 101 Dudley St, Providence, RI 02905.
Pediatrics. 2014 Jan;133(1):e45-53. doi: 10.1542/peds.2013-1628. Epub 2013 Dec 16.
To evaluate the accuracy of the Edinburgh Postnatal Depression Scale (EPDS) and 3 subscales for identifying postpartum depression among primiparous adolescent mothers.
Mothers enrolled in a randomized controlled trial to prevent postpartum depression completed a psychiatric diagnostic interview and the 10-item EPDS at 6 weeks, 3 months, and 6 months postpartum. Three subscales of the EPDS were assessed as brief screening tools: 3-item anxiety subscale (EPDS-3), 7-item depressive symptoms subscale (EPDS-7), and 2-item subscale (EPDS-2) that resemble the Patient Health Questionnaire-2. Receiver operating characteristic curves and the areas under the curves for each tool were compared to assess accuracy. The sensitivities and specificities of each screening tool were calculated in comparison with diagnostic criteria for a major depressive disorder. Repeated-measures longitudinal analytical techniques were used.
A total of 106 women contributed 289 postpartum visits; 18% of the women met criteria for incident postpartum depression by psychiatric diagnostic interview. When used as continuous measures, the full EPDS, EPDS-7, and EPDS-2 performed equally well (area under the curve >0.9). Optimal cutoff scores for a positive depression screen for the EPDS and EPDS-7 were lower (≥ 9 and ≥ 7, respectively) than currently recommended cutoff scores (≥ 10). At optimal cutoff scores, the EPDS and EPDS-7 both had sensitivities of 90% and specificities of >85%.
The EPDS, EPDS-7, and EPDS-2 are highly accurate at identifying postpartum depression among adolescent mothers. In primary care pediatric settings, the EPDS and its shorter subscales have potential for use as effective depression screening tools.
评估爱丁堡产后抑郁量表(EPDS)及其 3 个分量表识别初产妇青少年母亲产后抑郁的准确性。
参加预防产后抑郁随机对照试验的母亲在产后 6 周、3 个月和 6 个月时完成了精神病学诊断访谈和 10 项 EPDS。EPDS 的 3 个分量表被评估为简短的筛查工具:3 项焦虑分量表(EPDS-3)、7 项抑郁症状分量表(EPDS-7)和类似于患者健康问卷-2 的 2 项分量表(EPDS-2)。比较每个工具的接收者操作特征曲线和曲线下面积,以评估准确性。与重性抑郁障碍的诊断标准相比,计算了每种筛查工具的敏感度和特异性。使用重复测量纵向分析技术。
共有 106 名女性贡献了 289 次产后就诊;18%的女性通过精神病学诊断访谈符合产后抑郁的发病标准。当作为连续测量使用时,完整的 EPDS、EPDS-7 和 EPDS-2 的表现同样出色(曲线下面积>0.9)。EPDS 和 EPDS-7 阳性抑郁筛查的最佳截断分数较低(分别为≥9 和≥7),低于目前推荐的截断分数(≥10)。在最佳截断分数时,EPDS 和 EPDS-7 的敏感度均为 90%,特异性均>85%。
EPDS、EPDS-7 和 EPDS-2 非常准确地识别青少年母亲的产后抑郁。在初级保健儿科环境中,EPDS 及其较短的分量表具有作为有效抑郁筛查工具的潜力。