Bernstein Judith, Cheng Debbie M, Wang Na, Trilla Caitlin, Samet Jeffrey, Saitz Richard
Department of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts Department of Emergency Medicine, Boston University School of Medicine, Boston, Massachusetts
Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
Ann Fam Med. 2015 May-Jun;13(3):257-60. doi: 10.1370/afm.1750.
Should recreational drug use raise clinical concern? We examined the association between weekend-only recreational drug use at baseline (yes vs no) and any increase in recreational drug use frequency or severity over 6 months among primary care patients who screen positive for drug use. In the weekend-only recreational drug use group (52/483 [10.8%]), 54% (28/52) started using drugs on weekdays. Compared with use not limited to weekends, weekend-only use was associated with lower odds of increasing drug use frequency (AOR 0.48, P = 0.03) and lower odds (non-significant) of increasing severity (AOR 0.56, P = 0.07). Although weekend-only recreational drug use appears prognostically less severe, the findings nonetheless suggest that continued episodic monitoring may be clinically wise.
仅在周末使用消遣性药物是否应引起临床关注?我们研究了在药物使用筛查呈阳性的初级保健患者中,基线时仅在周末使用消遣性药物(是与否)与6个月内消遣性药物使用频率或严重程度的任何增加之间的关联。在仅在周末使用消遣性药物的组中(52/483 [10.8%]),54%(28/52)的人开始在工作日使用药物。与不限于周末的使用相比,仅在周末使用与药物使用频率增加的较低几率(优势比0.48,P = 0.03)和严重程度增加的较低几率(无统计学意义)(优势比0.56,P = 0.07)相关。尽管仅在周末使用消遣性药物在预后上似乎不太严重,但研究结果仍表明持续的定期监测在临床上可能是明智的。