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肺孢子菌肺炎滥用者的门诊治疗。

Outpatient treatment of PCP abusers.

作者信息

Gorelick D A, Wilkins J N, Wong C

机构信息

Alcohol & Drug Treatment Program Brentwood Division, West Los Angeles VA Medical Center, California 90073.

出版信息

Am J Drug Alcohol Abuse. 1989;15(4):367-74. doi: 10.3109/00952998908992797.

Abstract

Despite the persistence of phencyclidine (PCP) abuse as a public health problem in many urban areas of the United States, there are no published data on outpatient treatment outcome. We studied 37 unselected male PCP abusers (mean age 32 years, 73% Black, 19% married, 68% unemployed) who attended at least one outpatient treatment session at the Brentwood Division, West Los Angeles VA Medical Center. Subjects had smoked PCP for an average of 7 years, with 84% using it at least weekly (38% daily) and 76% using other drugs (alcohol, marijuana, or cocaine). All subjects reported psychological dependence on PCP (i.e., liking PCP use and difficulty stopping despite adverse consequences), while none reported a physiological withdrawal syndrome when stopping PCP use. Subjects stayed in treatment an average of 21 weeks (range 1-155 weeks), attending an average of 68% of the group meetings. PCP was detected in weekly urine samples 78% of the time, with verbal self-report of recent PCP use occurring before 29% of the group meetings. Four subjects (11%) achieved at least 1 year of abstinence, 10 (30%) transferred to residential treatment or a community recovery home, 16 (48%) dropped out of treatment, and two (6%) were jailed. Treatment outcome was not significantly associated with subject characteristics. Age was the only subject characteristic that significantly predicted length of stay (r = .40).

摘要

尽管在美国许多城市地区,苯环利定(PCP)滥用作为一个公共卫生问题一直存在,但尚无关于门诊治疗结果的公开数据。我们研究了37名未经挑选的男性PCP滥用者(平均年龄32岁,73%为黑人,19%已婚,68%失业),他们在西洛杉矶退伍军人事务医疗中心布伦特伍德分部至少参加了一次门诊治疗。这些受试者吸食PCP的平均时间为7年,84%的人至少每周使用一次(38%的人每天使用),76%的人还使用其他药物(酒精、大麻或可卡因)。所有受试者均报告对PCP存在心理依赖(即喜欢使用PCP且尽管有不良后果仍难以戒断),但无人报告在停用PCP时出现生理戒断综合征。受试者平均接受治疗21周(范围为1 - 155周),平均参加了68%的小组会议。在每周的尿液样本中,78%的时间检测到PCP,在29%的小组会议之前有近期使用PCP的口头自我报告。4名受试者(11%)实现了至少1年的戒断,10名(30%)转至住院治疗或社区康复之家,16名(48%)退出治疗,2名(6%)入狱。治疗结果与受试者特征无显著关联。年龄是唯一显著预测住院时间的受试者特征(r = 0.40)。

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