Schoeppner G, Chuang E L, Bird A C
Department of Clinical Ophthalmology, Moorfields Eye Hospital, London, England.
Am J Ophthalmol. 1989 Dec 15;108(6):683-5. doi: 10.1016/0002-9394(89)90861-1.
To identify the magnitude of risk of fellow-eye visual loss, we reviewed the records of 43 patients with unilateral central visual loss caused by a tear of detached retinal pigment epithelium seen in our institution over a period of one to 13 years. Loss of vision because of complications of age-related macular disease occurred in 16 of 43 patients (37%) in the first year, seven of 23 patients (30%) in the second year, and eight of 16 patients (50%) in the third year. An additional five patients lost visual acuity between the third and eighth years of follow-up. The cumulative risk of loss of visual acuity was 37% in one year, 59% in two years, and 80% in three years. Visual loss occurred in 29 of the 36 eyes as a result of a complication of retinal pigment epithelial detachment. The magnitude of risk to the fellow eye was greater than has been documented in unselected age-related macular degeneration.
为了确定对侧眼视力丧失的风险程度，我们回顾了我院在1至13年期间收治的43例因视网膜色素上皮脱离撕裂导致单侧中心视力丧失患者的记录。43例患者中，有16例（37%）在第一年因年龄相关性黄斑疾病并发症导致视力丧失，23例患者中有7例（30%）在第二年出现视力丧失，16例患者中有8例（50%）在第三年出现视力丧失。在随访的第三年至第八年期间，另有5例患者视力下降。视力丧失的累积风险在1年内为37%，2年内为59%，3年内为80%。36只眼中有29只因视网膜色素上皮脱离并发症而出现视力丧失。对侧眼的风险程度高于未筛选的年龄相关性黄斑变性患者的记录。
