State Environmental Protection Key Laboratory of Drinking Water Source Management and Technology, Shenzhen Key Laboratory of Drinking Water Source Safety Control, Shenzhen Research Academy of Environmental Sciences, Shenzhen 518001, China.
Xiamen Huaxia College, Xiamen 361005, China.
Talanta. 2015 Aug 15;141:80-5. doi: 10.1016/j.talanta.2015.03.056. Epub 2015 Apr 2.
A facile one-pot approach has been developed to prepare orange-emitting Cu nanoclusters (NCs) using tetrakis(hydroxymethyl)phosphonium chloride as a reducing agent and lipoic acid as a capping agent under an alkaline medium at room temperature. The as-prepared Cu NCs exhibited excellent water solubility, large Stokes shift, long lifetime and good dispersion. After the addition of polyvinyl pyrrolidone, the fluorescence intensity of dihydrolipoic acid-stabilized Cu NCs (DHLA-Cu NCs) was greatly enhanced, and their fluorescence signal remained stable for 5 weeks storage in the dark at room temperature. Based on H2O2-induced fluorescence quenching, DHLA-Cu NCs showed high sensitivity and selectivity for the detection of H2O2 in aqueous solution with a detection limit of 0.3μM, and were applied successfully to the detection of H2O2 in human urine samples.
一种简便的一锅法在室温碱性条件下，以四羟甲基氯化鏻为还原剂，硫辛酸为稳定剂，制备出了橙红色发光的铜纳米簇（NCs）。所制备的 Cu NCs 具有良好的水溶性、大的斯托克斯位移、长的寿命和良好的分散性。加入聚乙烯吡咯烷酮后，二氢硫辛酸稳定的 Cu NCs（DHLA-Cu NCs）的荧光强度大大增强，其荧光信号在黑暗室温下储存 5 周仍保持稳定。基于 H2O2 诱导的荧光猝灭，DHLA-Cu NCs 对水溶液中 H2O2 的检测表现出高灵敏度和选择性，检测限低至 0.3μM，并成功应用于人尿样中 H2O2 的检测。
