Gupta Shubham, Ding Laura, Granieri Michael, Le Ngoc-Bich, Peterson Andrew C
Department of Urology, University of Kentucky, Lexington,, Kentucky.
Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina.
Neurourol Urodyn. 2016 Aug;35(6):733-7. doi: 10.1002/nau.22790. Epub 2015 May 12.
To analyze the rates of incontinence procedures after radical prostatectomy, and define the variables associated with them.
We conducted an IRB approved retrospective review of patients with prostate cancer who underwent radical prostatectomy at a single institute from January 1998 to December 2012. Logistic regression and time to event analyses were performed to ascertain variables associated with receipt of incontinence procedure after prostatectomy.
Four thousand four hundred one men underwent radical prostatectomy (69.8% open, 30.1% laparoscopic or robotic) of whom 74.3% were white Caucasian and 22.1% were African-American. Overall, 165 (3.7%) patients underwent a total of 191 procedures for male urethral sling or artificial urinary sphincter placement. African-American men received fewer incontinence procedures than white Caucasian men (2.1% versus 4.3%, P = 0.001); and with a longer delay after prostatectomy than white Caucasian men (28.3 months versus 19.9 months, P = 0.029). Men who had a laparoscopic or robotic prostatectomy received an incontinence procedure earlier than men who had an open prostatectomy (17.6 months versus 24.4 months, P = 0.0001). On multivariate analysis, age at prostatectomy, diagnosis of incontinence, and race were independently associated with receiving an incontinence procedure.
The overall rate of incontinence surgery after radical prostatectomy is low at 3.7%. African-American men receive incontinence procedures at a lower rate and with a longer delay after prostatectomy than white Caucasian men. Further studies are needed to define the reasons for this racial disparity in urinary incontinence surgery in the prostate cancer survivor. Neurourol. Urodynam. 35:733-737, 2016. © 2015 Wiley Periodicals, Inc.
分析根治性前列腺切除术后尿失禁手术的发生率，并确定与之相关的变量。
我们对1998年1月至2012年12月在单一机构接受根治性前列腺切除术的前列腺癌患者进行了一项经机构审查委员会批准的回顾性研究。采用逻辑回归和事件发生时间分析来确定前列腺切除术后接受尿失禁手术相关的变量。
4401名男性接受了根治性前列腺切除术（69.8%为开放手术，30.1%为腹腔镜或机器人手术），其中74.3%为白人，22.1%为非裔美国人。总体而言，165名（3.7%）患者共接受了191次男性尿道悬带或人工尿道括约肌植入手术。非裔美国男性接受尿失禁手术的比例低于白人男性（2.1%对4.3%，P = 0.001）；且前列腺切除术后延迟时间比白人男性长（28.3个月对19.9个月，P = 0.029）。接受腹腔镜或机器人前列腺切除术的男性比接受开放前列腺切除术的男性更早接受尿失禁手术（17.6个月对24.4个月，P = 0.0001）。多因素分析显示，前列腺切除时的年龄、尿失禁诊断和种族与接受尿失禁手术独立相关。
根治性前列腺切除术后尿失禁手术的总体发生率较低，为3.7%。非裔美国男性接受尿失禁手术的比例较低，且前列腺切除术后延迟时间比白人男性长。需要进一步研究来确定前列腺癌幸存者尿失禁手术中这种种族差异的原因。《神经泌尿学与尿动力学》35:733 - 737，2016年。©2015威利期刊公司
