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PharmGKB summary: Efavirenz pathway, pharmacokinetics.

作者信息

McDonagh Ellen M, Lau Johnathan L, Alvarellos Maria L, Altman Russ B, Klein Teri E

机构信息

Departments of aGenetics bBioengineering, School of Medicine, Stanford University, Stanford, California, USA cDepartment of Immunology, University of Toronto, Toronto, Ontario, Canada.

出版信息

Pharmacogenet Genomics. 2015 Jul;25(7):363-76. doi: 10.1097/FPC.0000000000000145.

DOI:10.1097/FPC.0000000000000145
PMID:25966836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4461466/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ea/4461466/b04fc2c601f6/nihms-683146-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ea/4461466/b04fc2c601f6/nihms-683146-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ea/4461466/b04fc2c601f6/nihms-683146-f0001.jpg

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Pharmacogenomics. 2014 May;15(7):997-1006. doi: 10.2217/pgs.14.48.
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Secondary metabolism pathway polymorphisms and plasma efavirenz concentrations in HIV-infected adults with CYP2B6 slow metabolizer genotypes.HIV感染的携带CYP2B6慢代谢基因型的成年患者的次生代谢途径多态性与血浆依法韦仑浓度
J Antimicrob Chemother. 2014 Aug;69(8):2175-82. doi: 10.1093/jac/dku110. Epub 2014 Apr 11.
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Functional CYP2B6 variants and virologic response to an efavirenz-containing regimen in Port-au-Prince, Haiti.
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与印度尼西亚雅加达一家三级医院的 HIV 感染者长期保留抗逆转录病毒治疗相关的因素。
J Prev Med Public Health. 2024 May;57(3):252-259. doi: 10.3961/jpmph.23.512. Epub 2024 Apr 30.
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