Kuznetsova B A, Saprygin D B, Kuliev E A, Poplavskaia L M, Mikhaĭlova I L
Anesteziol Reanimatol. 1989 Sep-Oct(5):41-5.
It has been shown that the course and outcome of the early postoperative period in cardiosurgical patients are to a great extent related to the functioning of the adaptation systems under study and their interrelations. An essential role of sympathoadrenal system (SAS) in the control over hormonal body status has been established. It ensures, provided its activity is retained, interaction of other hormonal systems as a uniform functional mechanism in postoperative stress. Decreased activity and intrasystemic coordination of SAS combined with low activity of renin-angiotensin-aldosterone system and excessively activated hypophyseal-adrenal system in patients with postoperative complications are indicative of adaptation mechanism damage and are of negative prognostic value.
业已表明，心脏外科手术患者术后早期的病程及转归在很大程度上与所研究的适应系统的功能及其相互关系有关。交感肾上腺系统（SAS）在调控机体激素状态方面的重要作用已得到确认。在术后应激状态下，只要其活性得以维持，它就能确保其他激素系统作为一个统一的功能机制相互作用。术后并发症患者中，SAS活性降低及系统内协调性下降，再加上肾素 - 血管紧张素 - 醛固酮系统活性低下以及垂体 - 肾上腺系统过度激活，提示适应机制受损，具有负面预后价值。
