Hutchins Robert, Pignone Michael P, Sheridan Stacey L, Viera Anthony J
Health Care and Prevention MD-MPH Program, University of North Carolina at Chapel Hill School of Medicine and Gillings School of Global Public Health, Chapel Hill, North Carolina, USA.
Department of Medicine, Division of General Internal Medicine and Clinical Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
BMJ Open. 2015 May 11;5(5):e006505. doi: 10.1136/bmjopen-2014-006505.
The utility value attributed to taking pills for prevention can have a major effect on the cost-effectiveness of interventions, but few published studies have systematically quantified this value. We sought to quantify the utility value of taking pills used for prevention of cardiovascular disease (CVD).
Cross-sectional survey.
Central North Carolina.
708 healthcare employees aged 18 years and older.
Utility values for taking 1 pill/day, assessed using time trade-off, modified standard gamble and willingness-to-pay methods.
Mean age of respondents was 43 years (19-74). The majority of the respondents were female (83%) and Caucasian (80%). Most (80%) took at least 2 pills/day. Mean utility values for taking 1 pill/day using the time trade-off method were: 0.9972 (95% CI 0.9962 to 0.9980). Values derived from the standard gamble and willingness-to-pay methods were 0.9967 (0.9954 to 0.9979) and 0.9989 (95% CI 0.9986 to 0.9991), respectively. Utility values varied little across characteristics such as age, sex, race, education level or number of pills taken per day.
The utility value of taking pills daily in order to prevent an adverse CVD health outcome is approximately 0.997.
服用预防药物的效用价值可能对干预措施的成本效益产生重大影响，但很少有已发表的研究系统地量化这一价值。我们试图量化用于预防心血管疾病（CVD）的药物服用的效用价值。
横断面调查。
北卡罗来纳州中部。
708名18岁及以上的医疗保健员工。
使用时间权衡法、改良标准博弈法和支付意愿法评估每天服用1片药的效用价值。
受访者的平均年龄为43岁（19 - 74岁）。大多数受访者为女性（83%）和白种人（80%）。大多数人（80%）每天至少服用2片药。使用时间权衡法得出的每天服用1片药的平均效用价值为：0.9972（95%置信区间0.9962至0.9980）。通过标准博弈法和支付意愿法得出的值分别为0.9967（0.9954至0.9979）和0.9989（95%置信区间0.9986至0.9991）。效用价值在年龄、性别、种族、教育水平或每天服药数量等特征方面变化不大。
为预防不良心血管疾病健康结果而每日服药的效用价值约为0.997。
