Xu Peng, Han Hongjun, Zhuang Haifeng, Hou Baolin, Jia Shengyong, Wang Dexin, Li Kun, Zhao Qian
State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China.
State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China.
J Environ Sci (China). 2015 May 1;31:221-5. doi: 10.1016/j.jes.2014.09.034. Epub 2015 Feb 11.
The potential for degradation of five nitrogenous heterocyclic compounds (NHCs), i.e., imidazole, pyridine, indole, quinoline, and carbazole, was investigated under anoxic conditions with acclimated activated sludge. Results showed that NHCs with initial concentration of 50 mg/L could be completely degraded within 60 hr. The degradation of five NHCs was dependent upon the chemical structures with the following sequence: imidazole>pyridine>indole>quinoline>carbazole in terms of their degradation rates. Quantitative structure-biodegradability relationship studies of the five NHCs showed that the anoxic degradation rates were correlated well with highest occupied molecular orbital. Additionally, the active sites of NHCs identified by calculation were confirmed by analysis of intermediates using gas chromatography and mass spectrometry.
在缺氧条件下，利用驯化后的活性污泥研究了5种含氮杂环化合物（NHCs），即咪唑、吡啶、吲哚、喹啉和咔唑的降解潜力。结果表明，初始浓度为50 mg/L的NHCs可在60小时内完全降解。5种NHCs的降解取决于化学结构，降解速率顺序如下：咪唑>吡啶>吲哚>喹啉>咔唑。对这5种NHCs的定量结构-生物降解性关系研究表明，缺氧降解速率与最高占据分子轨道密切相关。此外，通过气相色谱和质谱分析中间体，证实了通过计算确定的NHCs的活性位点。
