Axén Iben
Intervention and Implementation Research, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Clin J Pain. 2016 Mar;32(3):254-9. doi: 10.1097/AJP.0000000000000249.
Pain has been found to be associated with poor sleep quality, awakenings, and shorter sleep time. There is a need to understand the relationship of pain and sleep over time to adequately manage the pain disorder and its consequences. The objectives of this study were to establish the prevalence of sleep disturbance in patients with acute or persistent low back pain (LBP), to investigate the correlation between pain and sleep disturbance and to explore the influence of pain on sleep disturbance.
Data from a prospective observational study of 233 patients with acute and persistent LBP were used. Twenty-six weekly pain reports and monthly (weeks 2, 6, 10, 14, 18, 22, and 26) sleep reports were collected with text messages. The prevalence of sleep disturbance, the correlation of pain and sleep disturbance, and the risk of reporting disturbed sleep after experiencing LBP were calculated.
Sleep disturbance was reported by 67% of the sample. Among patients with acute and persistent LBP, the prevalence was 55% and 76%, respectively. Measures of pain and sleep disturbance were significantly correlated. Compared with being pain free, the risk of reporting sleep disturbance after experiencing pain the previous week was significantly increased (relative risk=2.1 to 5.8), and a dose-response between the number of days with pain and the risk of sleep disturbance was found.
This study used repeated measures of both pain and sleep disturbance. The results were in line with previous research, confirming that sleep disturbance was found in the majority of patients with LBP. Pain and sleep measures were significantly correlated, and there was an increased risk of reporting sleep disturbance after experiencing LBP.
研究发现疼痛与睡眠质量差、觉醒及睡眠时间缩短有关。有必要了解疼痛与睡眠随时间的关系，以便充分管理疼痛障碍及其后果。本研究的目的是确定急性或持续性下腰痛（LBP）患者睡眠障碍的患病率，调查疼痛与睡眠障碍之间的相关性，并探讨疼痛对睡眠障碍的影响。
使用对233例急性和持续性LBP患者进行的前瞻性观察研究的数据。通过短信收集26份每周疼痛报告和每月（第2、6、10、14、18、22和26周）睡眠报告。计算睡眠障碍的患病率、疼痛与睡眠障碍的相关性以及经历LBP后报告睡眠障碍的风险。
67%的样本报告有睡眠障碍。在急性和持续性LBP患者中，患病率分别为55%和76%。疼痛和睡眠障碍指标显著相关。与无疼痛相比，前一周经历疼痛后报告睡眠障碍的风险显著增加（相对风险=2.1至5.8），并且发现疼痛天数与睡眠障碍风险之间存在剂量反应关系。
本研究对疼痛和睡眠障碍均采用了重复测量。结果与先前研究一致，证实大多数LBP患者存在睡眠障碍。疼痛和睡眠指标显著相关，并且经历LBP后报告睡眠障碍的风险增加。
