Institut für Organische Chemie, TU Braunschweig, Hagenring 30, 38106 Braunschweig (Germany) http://www.oc.tu-bs.de/schulz/index.html.
Speichergasse 8, 3150 Schwarzenburg (Switzerland).
Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7698-702. doi: 10.1002/anie.201501719. Epub 2015 May 12.
The snow flea Ceratophysella sigillata, a winter-active species of springtail, produces unique polychlorinated octahydroisocoumarins to repel predators. The structure of the major compound, sigillin A, was elucidated through isolation, spectroscopic analysis, and X-ray crystallography. Sigillin A showed high repellent activity in a bioassay with predatory ants. A promising approach for the total synthesis of members of this new class of natural compounds was also developed.
雪蚤 Ceratophysella sigillata 是一种冬季活跃的跳虫，它会产生独特的多氯化八氢异香豆素来抵御捕食者。主要化合物 sigillin A 的结构是通过分离、光谱分析和 X 射线晶体学阐明的。Sigillin A 在捕食性蚂蚁的生物测定中表现出高驱避活性。还开发了一种有前途的方法来全合成这种新型天然化合物的成员。
