Curtis J J, Nawarawong W, Walls J T, Schmaltz R A, Boley T, Madsen R, Anderson S K
Division of Cardiothoracic Surgery, University of Missouri, Columbia 65212.
Ann Thorac Surg. 1989 Dec;48(6):764-8. doi: 10.1016/0003-4975(89)90667-x.
We have reviewed chest roentgenograms of 745 patients before hospital dismissal after cardiac operations and serially to determine the incidence and prognosis of elevated hemidiaphragm and any relationship to the use of topical ice slush (TIS) in myocardial preservation. All patients had similar myocardial preservation techniques including moderate systemic hypothermia and 4 degrees C saline solution poured over the heart at aortic clamping. During a 12-month period, TIS was added to the saline bath. Two (2.4%) of 84 patients before TIS and 5 (2.5%) of 201 consecutive patients operated on since discontinuing TIS had elevated hemidiaphragm on the predismissal roentgenogram. Of 460 patients in whom TIS was employed, 109 (23.7%) had elevated hemidiaphragm (p less than 0.001). When TIS was employed, elevated hemidiaphragm developed in 72 (26%) of 280 patients without internal mammary artery takedown versus 13 of 33 patients (39.4%) with takedown of the internal mammary artery (p = 0.047). Ninety-nine patients with elevated hemidiaphragm were available for follow-up at 1 month, at which time 79 (79.8%) continued to have elevated diaphragm. At 1 year, 14 (21.9%) of 64 patients had persistent diaphragm elevation. We conclude that TIS predisposes to elevated diaphragm and that the incidence is increased when the internal mammary artery is harvested.
我们回顾了745例心脏手术后出院前的胸部X线片,并进行了系列观察,以确定半侧膈肌抬高的发生率和预后,以及其与心肌保护中使用局部冰屑(TIS)的关系。所有患者均采用相似的心肌保护技术,包括适度全身低温以及在主动脉阻断时将4℃盐水溶液浇在心脏上。在12个月的期间内,在盐水中加入了TIS。在使用TIS之前的84例患者中有2例(2.4%),自停止使用TIS后连续手术的201例患者中有5例(2.5%)在出院前的X线片上出现半侧膈肌抬高。在使用TIS的460例患者中,有109例(23.7%)出现半侧膈肌抬高(p<0.001)。使用TIS时,280例未进行胸廓内动脉游离的患者中有72例(26%)出现半侧膈肌抬高,而33例进行了胸廓内动脉游离的患者中有13例(39.4%)出现半侧膈肌抬高(p = 0.047)。99例半侧膈肌抬高的患者在1个月时可进行随访,此时79例(79.8%)仍有膈肌抬高。在1年时,64例患者中有14例(21.9%)持续存在膈肌抬高。我们得出结论,TIS易导致膈肌抬高,并且在游离胸廓内动脉时发生率会增加。