Hayano Koichi, Lee Sang Ho, Sahani Dushyant V
Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Indian J Radiol Imaging. 2015 Apr-Jun;25(2):121-8. doi: 10.4103/0971-3026.155835.
Morphologic methods such as the Response Evaluation Criteria in Solid Tumors (RECIST) are considered as the gold standard for response assessment in the management of cancer. However, with the increasing clinical use of antineoplastic cytostatic agents and locoregional interventional therapies in hepatocellular carcinoma (HCC), conventional morphologic methods are confronting limitations in response assessment. Thus, there is an increasing interest in new imaging methods for response assessment, which can evaluate tumor biology such as vascular physiology, fibrosis, necrosis, and metabolism. In this review, we discuss various novel imaging methods for response assessment and compare them with the conventional ones in HCC.
诸如实体瘤疗效评价标准（RECIST）之类的形态学方法被视为癌症管理中疗效评估的金标准。然而，随着抗肿瘤细胞毒性药物和局部区域介入治疗在肝细胞癌（HCC）临床应用的增加，传统形态学方法在疗效评估中面临局限性。因此，人们对用于疗效评估的新成像方法越来越感兴趣，这些新方法可以评估肿瘤生物学特性，如血管生理学、纤维化、坏死和代谢。在本综述中，我们讨论了用于疗效评估的各种新型成像方法，并将它们与HCC中的传统成像方法进行比较。
