Sekamova S M, Zykova L D
Arkh Patol. 1989;51(9):42-8.
It is established, on the basis of the autopsy material of I. M. Sechenov First Moscow Medical Institute for 1983-1987 (517 patients who died at the age of 40-89 years), that senile cerebral amyloidosis (SCA) is a local form of senile amyloidosis which occurs in 4.4% persons over 60 years of age. At the autopsy SCA is revealed in 21.4% cases, but the examination of the brain for amyloid increases the percent up to 78.6. Amyloid deposits are observed as senile plaques in the vessels of pia mater, plexus chorioideus and intracerebral vessels. Genetic factors in the SCA development can not be excluded.
根据1983 - 1987年莫斯科第一谢马什克国立医科大学的尸检材料(517例年龄在40 - 89岁之间死亡的患者)确定,老年脑淀粉样变性(SCA)是老年淀粉样变性的一种局部形式,发生于60岁以上人群中的4.4%。尸检时SCA在21.4%的病例中被发现,但对大脑进行淀粉样蛋白检查可将这一比例提高到78.6%。淀粉样蛋白沉积物在软脑膜、脉络丛和脑内血管中表现为老年斑。SCA发展中的遗传因素不能排除。