Oellers Patrick, Schneider Eric W, Fekrat Sharon, Mahmoud Tamer H, Mruthyunjaya Prithvi, Hahn Paul
Ophthalmic Surg Lasers Imaging Retina. 2015 Apr;46(4):451-6. doi: 10.3928/23258160-20150422-08.
To investigate cases of retained intraocular perfluoro-n-octane (PFO) after pars plana vitrectomy (PPV) for retinal detachment (RD).
Retrospective, noncomparative case series of six eyes with retained intraocular PFO after RD repair. Clinical data were supplemented with an experimental silicone eye model.
A cluster of six cases of retained intraocular PFO after PPV for RD repair were noted shortly after transitioning to valved cannulas. PFO was noted in the anterior chamber (AC) and/or vitreous and removed with AC paracentesis, AC wash-out, and/or PPV. A silicone eye model demonstrated that PFO levels are maintained anterior to cannula insertion with valved cannulas only.
The authors hypothesize that anterior PFO fill using valved cannulas can lead to sequestration within the AC, zonules, ciliary sulcus, ciliary teeth, and/or capsular bag. They suggest vigilance in not overfilling PFO, particularly when transitioning to use of valved cannulas, to minimize the risk of intraocular retention.
研究视网膜脱离（RD）行玻璃体切割术（PPV）后眼内全氟正辛烷（PFO）残留的病例。
对6例RD修复术后眼内PFO残留的病例进行回顾性、非对照病例系列研究。临床数据辅以实验性硅酮眼模型。
在改用带阀门的套管后不久，发现6例RD修复术后PPV后眼内PFO残留的病例。在前房（AC）和/或玻璃体中发现PFO，并通过前房穿刺、前房冲洗和/或PPV将其清除。硅酮眼模型显示，仅使用带阀门的套管时，PFO水平在套管插入前方得以维持。
作者推测，使用带阀门的套管使PFO在前房填充可导致其在AC、小带、睫状沟、睫状齿和/或囊袋内潴留。他们建议在填充PFO时保持警惕，避免过量填充，尤其是在改用带阀门的套管时，以尽量降低眼内残留的风险。
