Rossi Tommaso, Querzoli Giorgio, Angelini Giov Battista, Pellizzaro Camilla, Santoro Veronica, Rosari Giulia, Parravano Mariacristina, Steel David H, Romano Mario R
IRCCS-Fondazione Bietti ONLUS, 00184 Roma, Italy.
DICAAR, Università degli Studi di Cagliari, 09123 Cagliari, Italy.
Bioengineering (Basel). 2025 Apr 19;12(4):431. doi: 10.3390/bioengineering12040431.
To compare the efficiency of different manufacturers' valved cannulas (23G, 25G and 27G) (Alcon, Bausch & Lomb, BVI, DORC, Optikon) in maintaining intraocular pressure during vitrectomy by measuring leak pressure and the difference between set and actual intraocular pressure, under BSS and air infusion.
A BSS-filled reservoir was connected to a model eye allowing placement of leak-proof valved cannulas. A pressure sensor was interposed and the bottle height increased until leakage occurred. Air leakage was measured by connecting an air pump to different manufacturers' valved cannulas, inserted upside down to blow air against the valve with inside-out direction and immersed in soapy water to detect air bubbling.
The average BSS leaking pressure was 7.69 ± 0.77 mmHg for 23G, 9.92 ± 0.57 mmHg for 25G and 7.57 ± 0.80 mmHg for 27G. The 25G valved cannulas opened at higher pressure ( < 0.05). The difference between set and actual pressure in BSS never exceeded 4 mmHg. Leakage pressure under air ranged between 10 and 55 mmHg. The 27G valves opened at an average 47.2 ± 3.9 mmHg vs. 29.4 ± 7.2 for 25G and 24.1 ± 16.5 for 23G (27G vs. other gauges < 0.05). The difference between set and actual pressure under air infusion never exceeded 2 mmHg.
Despite significant differences, all tested valved cannulas satisfy safety criteria by keeping a surgically negligible difference between the set and actual intraocular pressure. The minimal leakage measure may act as a safety pressure damper under critical conditions.
通过测量在平衡盐溶液（BSS）和空气灌注下的漏液压力以及设定眼压与实际眼压之间的差异，比较不同制造商生产的带阀套管（23G、25G和27G）（爱尔康、博士伦、BVI、多克、奥普蒂康）在玻璃体切割术中维持眼压的效率。
将一个充满BSS的储液器连接到一个模型眼上，以便放置防漏带阀套管。插入一个压力传感器，然后升高瓶身高度直至发生漏液。通过将气泵连接到不同制造商生产的带阀套管上测量空气泄漏情况，套管倒置插入以向瓣膜内吹气，方向为由内向外，并浸入肥皂水中以检测气泡。
23G带阀套管的平均BSS漏液压力为7.69±0.77mmHg，25G为9.92±0.57mmHg，27G为7.57±0.80mmHg。25G带阀套管在较高压力下打开（<0.05）。BSS中设定压力与实际压力之间的差异从未超过4mmHg。空气灌注下的漏液压力在10至55mmHg之间。27G瓣膜平均在47.2±3.9mmHg时打开，25G为29.4±7.2mmHg，23G为24.1±16.5mmHg（27G与其他规格相比<0.05）。空气灌注下设定压力与实际压力之间的差异从未超过2mmHg。
尽管存在显著差异，但所有测试的带阀套管通过使设定眼压与实际眼压之间的差异在手术中可忽略不计，满足安全标准。最小漏液量测量在关键情况下可起到安全压力缓冲器的作用。
