Sancak Selim, Gursoy Tugba, Imamoglu Ebru Yalın, Karatekin Güner, Ovali Fahri
Zeynep Kamil Maternity and Children's Training and Research Hospital, Neonatal Intensive Care Unit, Istanbul, Turkey
Department of Pediatrics, Koç University School of Medicine, Neonatology Unit, Istanbul, Turkey.
J Child Neurol. 2016 Feb;31(2):138-44. doi: 10.1177/0883073815585350. Epub 2015 May 13.
The aim of this study was to evaluate cerebellar growth of preterm infants. Vermis height and transverse cerebellar diameter were measured by cranial ultrasonography in 38 preterm infants (27-32 weeks) at birth and term equivalent age. Measurements were compared with 40 term appropriate-for-gestational-age infants. Preterms at term equivalent age had larger vermis height than term infants (2.39 ± 0.25 cm vs 2.25 ± 0.18 cm, P = .005), whereas no significant difference was found in the transverse cerebellar diameter (5.32 ± 0.38 cm vs 5.44 ± 0.23 cm, P = .13). Vermis height and transverse cerebellar diameter of appropriate-for-gestational-age preterm infants (n = 29) were found larger than small-for-gestational-age ones (n = 9). Vermis height and transverse cerebellar diameter at term equivalent age of appropriate-for-gestational-age preterm infants born before and after 29 weeks of age showed no significant difference. Cerebellar growth is preserved in extreme preterms. However, being small for gestational age may have deleterious effects on cerebellar development.
本研究的目的是评估早产儿小脑的生长情况。对38例早产儿（27 - 32周）在出生时及足月相当年龄时进行头颅超声检查，测量小脑蚓部高度和小脑横径。将测量结果与40例足月适于胎龄儿进行比较。足月相当年龄的早产儿小脑蚓部高度大于足月儿（2.39±0.25 cm对2.25±0.18 cm，P = 0.005），而小脑横径无显著差异（5.32±0.38 cm对5.44±0.23 cm，P = 0.13）。适于胎龄的早产儿（n = 29）的小脑蚓部高度和小脑横径大于小于胎龄的早产儿（n = 9）。29周龄前后出生的适于胎龄早产儿在足月相当年龄时的小脑蚓部高度和小脑横径无显著差异。极早早产儿的小脑生长得以保留。然而，小于胎龄可能对小脑发育有有害影响。
