Higashi-Shingai Kayoko, Imai Takao, Takimoto Yasumitsu, Okumura Tomoko, Ohta Yumi, Morihana Tetsuo, Uno Atsuhiko, Watanabe Yoshiyuki, Horii Arata, Inohara Hidenori
Department of Otolaryngology, Suita Municipal Hospital , Suita, Osaka , Japan.
Acta Otolaryngol. 2015;135(10):1000-6. doi: 10.3109/00016489.2015.1043143. Epub 2015 May 14.
Contrast-enhanced magnetic resonance imaging (MRI) reveals variations in the endolymphatic morphology of the cystic lateral semicircular canal (CLSC) that correlate with inner ear function. This report is the first to suggest a relationship between the morphology and function of this common inner ear malformation in clinical cases.
This study investigated the radiological and functional findings of a common inner ear malformation using computed tomography (CT), gadolinium contrast-enhanced magnetic resonance imaging (MRI), caloric testing, and cervical and ocular vestibular evoked myogenic potential (VEMP) testing.
Four ears in three patients who were radiologically diagnosed with a CLSC and a normal cochlea on high-resolution CT and contrast-enhanced MRI were included. Semicircular canal and vestibular functions were analyzed using the caloric test and cervical and ocular VEMP testing.
Unilateral and bilateral cystic canals were found in two and one patients, respectively. In the first patient, the malformed vestibule and cystic space were separate on imaging, and perilymph filled the cystic space. The functional test results were normal. In the second patient, endolymph filled both cystic spaces, and the functional responses were poor. In the third patient, endolymph filled the cystic space, and the ear did not respond during functional testing.
对比增强磁共振成像（MRI）显示囊性外侧半规管（CLSC）的内淋巴形态存在变异，这些变异与内耳功能相关。本报告首次在临床病例中提示这种常见内耳畸形的形态与功能之间存在关联。
本研究使用计算机断层扫描（CT）、钆对比增强磁共振成像（MRI）、冷热试验以及颈性和眼性前庭诱发肌源性电位（VEMP）测试，对一种常见内耳畸形的影像学和功能学表现进行了研究。
纳入3例患者的4只耳朵，这些患者在高分辨率CT和对比增强MRI上经影像学诊断为CLSC且耳蜗正常。使用冷热试验以及颈性和眼性VEMP测试分析半规管和前庭功能。
分别在2例和1例患者中发现了单侧和双侧囊性半规管。在首例患者中，畸形的前庭和囊性间隙在影像学上是分开的，外淋巴充满囊性间隙。功能测试结果正常。在第2例患者中，内淋巴充满两个囊性间隙，功能反应较差。在第3例患者中，内淋巴充满囊性间隙，该耳在功能测试期间无反应。
