未结合配体的甲状腺激素受体在早期胚胎发育过程中调节生长和发育时间：甲状腺激素受体作用的双重功能机制的证据。
Unliganded TRs regulate growth and developmental timing during early embryogenesis: evidence for a dual function mechanism of TR action.
作者信息
Yen Paul M
机构信息
Laboratory of Hormonal Regulation, Cardiovascular and Metabolic Disorders Program, 8 College Road, Level 8D14, Singapore, 169857 Singapore.
出版信息
Cell Biosci. 2015 Mar 2;5:8. doi: 10.1186/2045-3701-5-8. eCollection 2015.
Abstract
Recent genetic studies in the anuran Xenopus tropicalis reveal surprising new roles of thyroid hormone receptor in regulating growth and developmental timing in the absence of thyroid hormone.
摘要
近期对热带爪蟾这一蛙类的遗传学研究揭示了甲状腺激素受体在缺乏甲状腺激素时调节生长和发育时间方面令人惊讶的新作用。
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本文引用的文献
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Epigenetic regulation of thyroid hormone-induced adult intestinal stem cell development during anuran metamorphosis.在两栖动物变态过程中，甲状腺激素诱导的成年肠道干细胞发育的表观遗传调控。
Cell Biosci. 2014 Nov 28;4:73. doi: 10.1186/2045-3701-4-73. eCollection 2014.
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Unliganded thyroid hormone receptor α regulates developmental timing via gene repression in Xenopus tropicalis.无配体甲状腺激素受体 α 通过基因抑制调节 Xenopus tropicalis 的发育时间。
Endocrinology. 2015 Feb;156(2):735-44. doi: 10.1210/en.2014-1554. Epub 2014 Dec 2.
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Unliganded thyroid hormone receptor α controls developmental timing in Xenopus tropicalis.无配体甲状腺激素受体α控制 Xenopus tropicalis 的发育时间。
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Molecular and developmental analyses of thyroid hormone receptor function in Xenopus laevis, the African clawed frog.非洲爪蟾（非洲爪蟾）甲状腺激素受体功能的分子与发育分析。
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