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Amlodipine/valsartan single pill combination therapy in Chinese patients not controlled on previous monotherapy.

作者信息

Düsing Rainer

机构信息

Hypertoniezentrum Bonn, Schwerpunktpraxis, Bonn, Germany.

出版信息

J Thorac Dis. 2015 Apr;7(4):562-3. doi: 10.3978/j.issn.2072-1439.2015.03.16.

DOI:10.3978/j.issn.2072-1439.2015.03.16
PMID:25973219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4419297/
Abstract
摘要

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Amlodipine/valsartan single pill combination therapy in Chinese patients not controlled on previous monotherapy.氨氯地平/缬沙坦单片复方制剂治疗既往单药治疗未达标的中国患者。
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[Efficacy and safety of the single pill combination of valsartan 80 mg plus amlodipine 5 mg in mild to moderate essential hypertensive patients without adequate blood pressure control by monotherapy].缬沙坦80毫克加氨氯地平5毫克单片复方制剂治疗单药治疗血压控制不佳的轻至中度原发性高血压患者的疗效和安全性
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Comparison of single-pill strategies first line in hypertension: perindopril/amlodipine versus valsartan/amlodipine.高血压一线单药治疗策略比较：培哚普利/氨氯地平与缬沙坦/氨氯地平对比
J Hypertens. 2015 Feb;33(2):401-11. doi: 10.1097/HJH.0000000000000409.
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Comparison of real-world adherence, healthcare resource utilization and costs for newly initiated valsartan/amlodipine single-pill combination versus angiotensin receptor blocker/calcium channel blocker free-combination therapy.比较新起始缬沙坦/氨氯地平单片复方与血管紧张素受体阻滞剂/钙通道阻滞剂自由联合治疗的真实世界依从性、医疗资源利用和成本。
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Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension.两项多中心、为期8周、随机、双盲、安慰剂对照、平行组研究，评估氨氯地平和缬沙坦联合用药及单药治疗对轻度至中度原发性高血压成年患者的疗效和耐受性。
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Real-world effectiveness of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide in high-risk patients and other subgroups.氨氯地平/缬沙坦及氨氯地平/缬沙坦/氢氯噻嗪在高危患者及其他亚组中的真实世界有效性。
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Amlodipine/valsartan single-pill combination: a prospective, observational evaluation of the real-life safety and effectiveness in the routine treatment of hypertension.氨氯地平/缬沙坦单片复方制剂：一项前瞻性、观察性研究，评估其在高血压常规治疗中的真实安全性和有效性。
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Efficacy and tolerability of amlodipine/valsartan combination therapy in hypertensive patients not adequately controlled on valsartan monotherapy.氨氯地平/缬沙坦联合治疗对缬沙坦单药治疗控制不佳的高血压患者的疗效和耐受性
Curr Med Res Opin. 2009 Feb;25(2):315-24. doi: 10.1185/03007990802630588.

引用本文的文献

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Formulations of Amlodipine: A Review.氨氯地平制剂：综述
J Pharm (Cairo). 2016;2016:8961621. doi: 10.1155/2016/8961621. Epub 2016 Oct 16.

本文引用的文献

1
Efficacy and safety of valsartan/amlodipine single-pill combination in 11,422 Chinese patients with hypertension: an observational study.缬沙坦/氨氯地平单片复方制剂治疗11422例中国高血压患者的疗效和安全性：一项观察性研究
Adv Ther. 2014 Jul;31(7):762-75. doi: 10.1007/s12325-014-0132-x. Epub 2014 Jul 2.
2
Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension.美国高血压学会和国际高血压学会声明：社区高血压管理临床实践指南
J Hypertens. 2014 Jan;32(1):3-15. doi: 10.1097/HJH.0000000000000065.
3
2013 ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).2013年欧洲高血压学会（ESH）和欧洲心脏病学会（ESC）动脉高血压管理指南：欧洲高血压学会（ESH）和欧洲心脏病学会（ESC）动脉高血压管理特别工作组
J Hypertens. 2013 Jul;31(7):1281-357. doi: 10.1097/01.hjh.0000431740.32696.cc.
4
Optimizing blood pressure control through the use of fixed combinations.通过使用固定复方制剂优化血压控制。
Vasc Health Risk Manag. 2010 May 25;6:321-5. doi: 10.2147/vhrm.s9989.
5
Efficacy of the combination of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy: the Exforge in Failure after Single Therapy (EX-FAST) study.氨氯地平和缬沙坦联合用药对既往单药治疗未控制的高血压患者的疗效：单药治疗失败后使用氨氯地平缬沙坦片（EX-FAST）研究
J Clin Hypertens (Greenwich). 2008 Mar;10(3):185-94. doi: 10.1111/j.1751-7176.2008.07516.x.
6
Adherence to medication.药物依从性
N Engl J Med. 2005 Aug 4;353(5):487-97. doi: 10.1056/NEJMra050100.