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一例最初被诊断为肺癌的转移性直肠鳞状细胞癌病例。

A case of metastatic rectal squamous cell carcinoma initially diagnosed as lung cancer.

作者信息

Win Aung Zaw, Aparici Carina Mari

机构信息

Department of Radiology, San Francisco VA Medical Center, San Francisco, California, USA.

Department of Radiology, University California San Francisco (UCSF), San Francisco, California, USA.

出版信息

J Clin Imaging Sci. 2015 Apr 30;5:22. doi: 10.4103/2156-7514.156125. eCollection 2015.

DOI:10.4103/2156-7514.156125
PMID:25973286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4421885/
Abstract

Squamous cell carcinoma (SCC) of the rectum is extremely rare with a reported incidence of only 0.025-0.1% of all colorectal tumors. The patient was a 68-year-old man who presented with fatigue, dry cough, shortness of breath, and unintentional weight loss. A chest CT revealed a left suprahilar mass suspected to be lung cancer and an initial diagnosis of primary lung cancer was made. However, fluorodeoxyglucose positron emission tomography and computed tomography (FDG-PET/CT) exam revealed an intensely hypermetabolic rectal mass which turned out to be rectal squamous cell carcinoma. This is the first report that shows FDG-PET/CT images of rectal squamous cell carcinoma metastasis to the skin, muscle, bone, and lung. Use of PET/CT in the initial diagnosis of non-resectable rectal cancers may avoid unnecessary surgery.

摘要

直肠鳞状细胞癌(SCC)极为罕见,据报道其发病率仅占所有结直肠肿瘤的0.025 - 0.1%。该患者为一名68岁男性,表现为疲劳、干咳、气短和非故意体重减轻。胸部CT显示左肺门上方有一肿块,怀疑为肺癌,初步诊断为原发性肺癌。然而,氟脱氧葡萄糖正电子发射断层扫描和计算机断层扫描(FDG-PET/CT)检查发现直肠有一高代谢肿块,结果为直肠鳞状细胞癌。这是首份展示直肠鳞状细胞癌转移至皮肤、肌肉、骨骼和肺部的FDG-PET/CT图像的报告。PET/CT用于不可切除直肠癌的初始诊断可能避免不必要的手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baf6/4421885/78e583d05afb/JCIS-5-22-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baf6/4421885/1cee79191efa/JCIS-5-22-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baf6/4421885/78e583d05afb/JCIS-5-22-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baf6/4421885/1cee79191efa/JCIS-5-22-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baf6/4421885/78e583d05afb/JCIS-5-22-g003.jpg

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Rectal cancer level significantly affects rates and patterns of distant metastases among rectal cancer patients post curative-intent surgery without neoadjuvant therapy.在未接受新辅助治疗的直肠癌患者中,直肠癌分期显著影响根治性手术后远处转移的发生率和模式。
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Eur J Cancer. 2008 Nov;44(16):2340-3. doi: 10.1016/j.ejca.2008.07.004. Epub 2008 Aug 15.
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